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1B1
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Histone deacetylase inhibitors valproate and trichostatin A are toxic to neuroblastoma cells and modulate cytochrome P450 1A1, 1B1 and 3A4 expression in these cells
2009 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport, Faculty of Mathematics and Physics
publication
Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1
2012 |
Faculty of Science
publication
Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1
2016 |
Faculty of Science
publication
Serum Levels of Aryl Hydrocarbon Receptor, Cytochromes P450 1A1 and 1B1 in Patients with Exacerbated Psoriasis Vulgaris
2018 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
New insights in bilirubin metabolism and their clinical implications
2013 |
Third Faculty of Medicine
publication
Genome-wide association study to characterize serum bilirubin elevations in patients with HCV treated with GS-9256, an HCV NS3 serine protease inhibitor
2014 |
First Faculty of Medicine
publication
The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers
2016 |
Faculty of Science
publication
Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes
2021 |
Faculty of Science
publication
Exposure to endocrine disruptors 17alpha-ethinylestradiol and estradiol influences cytochrome P450 1A1-mediated genotoxicity of benzo[a]pyrene and expression of this enzyme in rats
2018 |
Faculty of Science
publication
Ellipticine oxidation and DNA adduct formation in human hepatocytes is catalyzed by human cytochromes P450 and enhanced by cytochrome b5
2012 |
Faculty of Science
publication
Association between exposure-relevant polymorphisms in CYP1B1,EPHX1,NQ01,GSTM1,GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population
2010 |
Second Faculty of Medicine, First Faculty of Medicine
publication
Expression Levels of Enzymes Metabolizing an Anticancer Drug Ellipticine Determined by Electromigration Assays Influence its Cytotoxicity to Cancer Cells - A Comparative Study
2014 |
Faculty of Science, Second Faculty of Medicine
publication
Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b(5) Activity
2020 |
Faculty of Science
publication
RNA expression of cytochrome P450 in breast cancer patients
2007 |
Second Faculty of Medicine, First Faculty of Medicine, Central Library of Charles University
publication
Genetic heterogeneity and minor CYP1B1 involvement in the molecular basis of primary congenital glaucoma in Gypsies
2008 |
Second Faculty of Medicine
publication
RNA expression of cytochrome P450 in breast cancer patients
2007 |
Second Faculty of Medicine
publication
Electrochemical Determination of Enzymes Metabolizing Ellipticine in Thyroid Cancer Cells - a Tool to Explain the Mechanism of Ellipticine Toxicity to these Cells
2013 |
Faculty of Science, Second Faculty of Medicine
publication
Electrochemical Determination of Enzymes Metabolizing Ellipticine in Thyroid Cancer Cells - a Tool to Explain the Mechanism of Ellipticine Toxicity to these Cells
2013 |
Publication without faculty affiliation
publication
CYP1B1 gene polymorphism modifies pancreatic cancer risk but not survival
2010 |
First Faculty of Medicine
publication
Cytochrome P450-and peroxidase-mediated oxidation of anticancer alkaloid ellipticine dictates its anti-tumor efficiency
2011 |
Faculty of Science
publication
Metabolic Gene Variants Associated with Chromosomal Aberrations in Healthy Humans
2015 |
Second Faculty of Medicine, First Faculty of Medicine
publication
A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches
2015 |
Faculty of Science
publication
Clinical correlation of lymphovascular invasion and Silva pattern of invasion in early-stage endocervical adenocarcinoma: proposed binary Silva classification system
2022 |
First Faculty of Medicine
publication
MILACC study: could undetected lymph node micrometastases have impacted recurrence rate in the LACC trial?
2023 |
First Faculty of Medicine