- Dinaciclib, a cyclin-dependent kinase inhibitor, is a substrate of human ABCB1 and ABCG2 and an inhibitor of human ABCC1 in vitro2015 | Faculty of Pharmacy in Hradec Králové
- Importance of ABCC1 for cancer therapy and prognosis2014 | First Faculty of Medicine, Faculty of Medicine in Pilsen
- Encorafenib Acts as a Dual-Activity Chemosensitizer through Its Inhibitory Effect on ABCC1 Transporter In Vitro and Ex Vivo2022 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Non-Coding Polymorphisms in Nucleotide Binding Domain 1 in ABCC1 Gene Associate with Transcript Level and Survival of Patients with Breast Cancer2014 | First Faculty of Medicine, Second Faculty of Medicine, Third Faculty of Medicine
- Interactions of cyclin-dependent kinase inhibitors AT-7519, flavopiridol and SNS-032 with ABCB1, ABCG2 and ABCC1 transporters and their potential to overcome multidrug resistance in vitro2015 | Faculty of Pharmacy in Hradec Králové
- Talazoparib Does Not Interact with ABCB1 Transporter or Cytochrome P450s, but Modulates Multidrug Resistance Mediated by ABCC1 and ABCG2: An in Vitro and Ex Vivo Study2022 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter2022 | Faculty of Pharmacy in Hradec Králové
- Tazemetostat synergistically combats multidrug resistance by the unique triple inhibition of ABCB1, ABCC1, and ABCG2 efflux transporters in vitro and ex vivo2023 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- In vitro function and in situ localization of Multidrug Resistance-associated Protein (MRP)1 (ABCC1) suggest a protective role against methyl mercury-induced oxidative stress in the human placenta2020 | Faculty of Pharmacy in Hradec Králové
- Physicochemistry shapes bioactivity landscape of pan-ABC transporter modulators: Anchor point for innovative Alzheimer's disease therapeutics2022 | Publication without faculty affiliation
- ABC transporters are predictors of treatment failure in acute myeloid leukaemia2024 | First Faculty of Medicine, Faculty of Science
- Modulation of bilirubin neurotoxicity by the Abcb1 transporter in the Ugt1(-/-) lethal mouse model of neonatal hyperbilirubinemia2017 | First Faculty of Medicine
- The expression profile of ATP-binding cassette transporter genes in breast carcinoma2013 | First Faculty of Medicine, Central Library of Charles University
- Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters2019 | Faculty of Pharmacy in Hradec Králové
- Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance2019 | Faculty of Pharmacy in Hradec Králové
- Entrectinib reverses cytostatic resistance through the inhibition of ABCB1 efflux transporter, but not the CYP3A4 drug-metabolizing enzyme2020 | Faculty of Pharmacy in Hradec Králové
- Isocitrate dehydrogenase 2 inhibitor enasidenib synergizes daunorubicin cytotoxicity by targeting aldo-keto reductase 1C3 and ATP-binding cassette transporters2022 | Faculty of Pharmacy in Hradec Králové
- The association of taxane resistance genes with the clinical course of ovarian carcinoma2013 | First Faculty of Medicine, Second Faculty of Medicine
- Germline and somatic genetic variability of oxysterol-related genes in breast cancer patients with early disease of the luminal subtype2022 | First Faculty of Medicine, Faculty of Medicine in Pilsen, Second Faculty of Medicine
- Dabrafenib inhibits ABCG2 and cytochrome P450 isoenzymes; potential implications for combination anticancer therapy2022 | Faculty of Pharmacy in Hradec Králové
- Differences in Transcript Levels of ABC Transporters Between Pancreatic Adenocarcinoma and Nonneoplastic Tissues2013 | First Faculty of Medicine, Central Library of Charles University
- Bruton's Tyrosine Kinase Inhibitor Zanubrutinib Effectively Modulates Cancer Resistance by Inhibiting Anthracycline Metabolism and Efflux2022 | Faculty of Pharmacy in Hradec Králové
- Brivanib Exhibits Potential for Pharmacokinetic Drug-Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes2019 | Faculty of Pharmacy in Hradec Králové
- Multidrug Resistance Modulation Activity of Silybin Derivatives and Their Anti-inflammatory Potential2020 | Faculty of Medicine in Pilsen
- The role of ABC transporters in progression and clinical outcome of colorectal cancer2012 | First Faculty of Medicine, Faculty of Medicine in Pilsen