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AKR1B10
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Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment
2015 |
Faculty of Pharmacy in Hradec Králové
publication
Purification and characterization of AKR1B10 from human liver: role in carbonyl reduction of xenobiotics
2006 |
Faculty of Pharmacy in Hradec Králové
publication
IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors
2016 |
Faculty of Science
publication
Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29
2011 |
Faculty of Pharmacy in Hradec Králové
publication
Inhibition of AKR1B10-mediated metabolism of daunorubicin as a novel off-target effect for the Bcr-Abl tyrosine kinase inhibitor dasatinib
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Purification and characterization of an oxidoreductase in human liver cytosol participating in carbonyl reduction of the tobacco-specific nitrosamine NNK
Publication without faculty affiliation
publication
Role of carbonyl reducing enzymes in the phase I biotransformation of the non-steroidal anti-inflammatory drug nabumetone in vitro
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Reductive metabolism of tiaprofenic acid by the human liver and recombinant carbonyl reducing enzymes
2017 |
Faculty of Pharmacy in Hradec Králové
publication
Carbonyl-reducing enzymes as targets of a drug-immobilised affinity carrier
2015 |
Faculty of Pharmacy in Hradec Králové
publication
Interactions of antileukemic drugs with daunorubicin reductases: could reductases affect the clinical efficacy of daunorubicin chemoregimens?
2020 |
Faculty of Pharmacy in Hradec Králové
publication
Buparlisib is a novel inhibitor of daunorubicin reduction mediated by aldo-keto reductase 1C3
2019 |
Faculty of Pharmacy in Hradec Králové