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Antisense oligonucleotide
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publication
Antisense oligonucleotide eluforsen is safe and improves respiratory symptoms in F508DEL cystic fibrosis
2020 |
Second Faculty of Medicine
publication
Monitoring of labeled antisense oligonucleotides within living cells by using a multifrequency phase/modulation approach for fluorescence lifetime measurements
2003 |
Faculty of Mathematics and Physics
publication
A frequency domain phase/modulation approach for measuring of fluorescence lifetimes of stained antisense oligonucleotides in interaction with living cells
2002 |
Publication without faculty affiliation
publication
Impact of the internucleotide linkage modification on the conformation and structural properties of 'antisense' oligonucleotides: Raman spectroscopy
1997 |
Faculty of Mathematics and Physics
publication
Hydrophilic interaction liquid chromatography with mass spectrometry for the separation and identification of antisense oligonucleotides impurities and nusinersen metabolites
2024 |
Faculty of Science
publication
Gene-selective treatment approaches for Huntington's disease
2020 |
First Faculty of Medicine
publication
Complex between Human RNase HI and the phosphonate-DNA/RNA duplex: Molecular dynamics study
2013 |
Faculty of Mathematics and Physics
publication
Disease-modifying treatment approaches in Huntington disease: Past and future
2022 |
First Faculty of Medicine
publication
Whole genome sequencing for USH2A-associated disease reveals several pathogenic deep-intronic variants that are amenable to splice correction
2023 |
First Faculty of Medicine
publication
RNA-directed off/on switch of RNase H activity using boronic ester formation
2017 |
Faculty of Mathematics and Physics
publication
Intracellular Uptake of Modified Oligonucleotide Studied by Two Fluorescence Techniques
2004 |
Faculty of Mathematics and Physics
publication
The use of inactivation of the ANGPTL3 molecule in the treatment of dyslipidemia
2022 |
Faculty of Medicine in Hradec Králové
publication
Study of Cellular Uptake of Modified Oligonucleotides by Using Time-Resolved Microspectrofluorimetry and Florescence Imaging
2012 |
Faculty of Mathematics and Physics
publication
Frequency domain fluorescence microspectrometry: Application to cellular uptake and drug distribution
2010 |
Faculty of Mathematics and Physics
publication
Pharmacotherapy of dyslipidemias - an overview of new findings
2021 |
First Faculty of Medicine
publication
Cellular uptake of modified oligonucleotides enhanced by porphyrins studied by time-resolved microspectrofluorimetry and fluorescence imaging techniques
2011 |
Faculty of Mathematics and Physics
publication
Hypertriglyceridemia - today and tomorrow
2020 |
First Faculty of Medicine
publication
Will we change the strategy of anticoagulation therapy?
2022 |
Third Faculty of Medicine
publication
Fluorescence Characterization of Gold Modified Liposomes with Antisense N-myc DNA Bound to the Magnetisable Particles with Encapsulated Anticancer Drugs (Doxorubicin, Ellipticine and Etoposide)
2016 |
Second Faculty of Medicine, Faculty of Science
publication
Randomized, placebo-controlled trial of mipomersen in patients with severe hypercholesterolemia receiving maximally tolerated lipid-lowering therapy
2012 |
First Faculty of Medicine
publication
5 '-O-Methylphosphonate nucleic acids-new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes
2014 |
Faculty of Mathematics and Physics
publication
AT(1) receptor antisense therapy transiently lowers blood pressure in Ren-2 transgenic rats
2007 |
Second Faculty of Medicine
publication
Antisense Therapy for a Common Corneal Dystrophy Ameliorates TCF4 Repeat Expansion-Mediated Toxicity
2018 |
First Faculty of Medicine
publication
Recombinant Adeno-Associated Virus Serotype 9 Gene Therapy in Spinal Muscular Atrophy
2021 |
Second Faculty of Medicine
publication
Position of lipoprotein apheresis in present
2015 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Gene therapy in radiation oncology
2020 |
First Faculty of Medicine
publication
Cobalt bis(dicarbollide) is a DNA-neutral pharmacophore
2023 |
Faculty of Science
publication
Nanotechnology - new trends in the treatment of brain tumours
2014 |
Faculty of Medicine in Hradec Králové