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Blood-brain barrier (BBB)
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publication
Signs of Myelin Impairment in Cerebrospinal Fluid After Osmotic Opening of the Blood-Brain Barrier in Rats
2015 |
First Faculty of Medicine
publication
Blood-brain barrier in vitro models as tools in drug discovery: Assessment of the transport ranking of antihistaminic drugs
2012 |
Faculty of Pharmacy in Hradec Králové
publication
Lack of Interactions between Breast Cancer Resistance Protein (BCRP/ABCG2) and Selected Antiepileptic Agents
+1
2006 |
Faculty of Medicine in Hradec Králové
publication
Lack of Interactions between Breast Cancer Resistance Protein (BCRP/ABCG2) and Selected Antiepileptic Agents
2006 |
First Faculty of Medicine
publication
CT imaging and spontaneous behavior analysis after osmotic blood-brain barrier opening in Wistar rat
2014 |
First Faculty of Medicine
publication
In Vitro Inhibitory Effects of 8-O-Demethylmaritidine and Undulatine on Acetylcholinesterase and Their Predicted Penetration across the Blood-Brain Barrier
2015 |
Publication without faculty affiliation
publication
A Transgenic Approach to Identify Thyroxine Transporter-Expressing Structures in Brain Development
2011 |
First Faculty of Medicine
publication
Novel Tacrine-Scutellarin hybrids as multipotent Anti-Alzheimer's agents: Design, synthesis and biological evaluation
2017 |
Publication without faculty affiliation
publication
Derivatives of montanine-type alkaloids and their implication for the treatment of Alzheimer's disease: Synthesis, biological activity and in silico study
2021 |
Faculty of Pharmacy in Hradec Králové
publication
PiB-Conjugated, Metal-Based Imaging Probes: Multimodal Approaches for the Visualization of beta-Amyloid Plaques
2013 |
Faculty of Science
publication
Derivatives of the beta-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer's Disease
2019 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
A Multidisciplinary Hypothesis about Serotonergic Psychedelics. Is it Possible that a Portion of Brain Serotonin Comes From the Gut?
2022 |
First Faculty of Medicine, Faculty of Medicine in Pilsen
publication
Acetylcholinesterase inhibitors used or tested in Alzheimer’s disease therapy; their passive diffusion through blood brain barrier: In vitro study
2013 |
Publication without faculty affiliation
publication
Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease
2016 |
Publication without faculty affiliation
publication
/Gd-Tracker/ a software for blood-brain barrier permeability assessment
2017 |
Second Faculty of Medicine
publication
Alkaloids of Zephyranthes citrina (Amaryllidaceae) and their implication to Alzheimer's disease: Isolation, structural elucidation and biological activity
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Cellular Internalization and Inhibition Capacity of New Anti-Glioma Peptide Conjugates: Physicochemical Characterization and Evaluation on Various Monolayer- and 3D-Spheroid-Based in Vitro Platforms
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Molecular Modeling and In Vitro Studies of a Neutral Oxime as a Potential Reactivator for Acetylcholinesterase Inhibited by Paraoxon
2018 |
Faculty of Medicine in Hradec Králové
publication
Current approaches to enhancing oxime reactivator delivery into the brain
2019 |
Publication without faculty affiliation
publication
Functionalized aromatic esters of the Amaryllidaceae alkaloid haemanthamine and their in vitro and in silico biological activity connected to Alzheimer's disease
2020 |
Faculty of Pharmacy in Hradec Králové
publication
Effect of P-glycoprotein on the availability of oxime reactivators in the brain
2020 |
Publication without faculty affiliation
publication
Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease
2022 |
Faculty of Pharmacy in Hradec Králové
publication
In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier
2019 |
Publication without faculty affiliation
publication
Aromatic Esters of the Crinane Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Butyrylcholinesterase
2020 |
Faculty of Pharmacy in Hradec Králové
publication
Strategies for enhanced bioavailability of oxime reactivators in the central nervous system
2023 |
Publication without faculty affiliation
publication
Protective associations of HDL with blood-brain barrier injury in multiple sclerosis patients
2015 |
First Faculty of Medicine
publication
Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-D-Aspartate Receptor Antagonists
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Science