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Carbenium ions
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The unexpected gas-phase reactivity of the CH3OH adduct of Michler?s hydrol blue: Proton-shuttle catalysis and stepwise radical expulsions
2007 |
Faculty of Science
publication
Genotoxic mechanisms for the carcinogenicity of the environmental pollutants and carcinogens o-anisidine and 2-nitroanisole follow from adducts generated by their metabolite N-(2-methoxyphenyl)-hydroxylamine with deoxyguanosine in DNA
2009 |
Faculty of Science, First Faculty of Medicine, Faculty of Mathematics and Physics
publication
Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine
2007 |
Second Faculty of Medicine
publication
Human cytochrome-P450 enzymes metabolize N-(2-methoxyphenyl)hydroxylamine, a metabolite of the carcinogens o-anisidine and o-nitroanisole, thereby dictating its genotoxicity
2011 |
Faculty of Science
publication
Cytochrome P450-and peroxidase-mediated oxidation of anticancer alkaloid ellipticine dictates its anti-tumor efficiency
2011 |
Faculty of Science
publication
Formation, Persistence, and Identification of DNA Adducts Formed by the Carcinogenic Environmental Pollutant o-Anisidine in Rats
2012 |
Faculty of Science, Central Library of Charles University
publication
Activation and detoxification metabolism of urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone by rat and mouse hepatic microsomes
2012 |
Faculty of Science