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Chk1
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Checkpoint Kinase 1 Is a Key Signal Transducer of DNA Damage in the Early Mammalian Cleavage Embryo
2023 |
First Faculty of Medicine
publication
Haemanthamine alters sodium butyrate-induced histone acetylation, p21(WAF1/Cip1) expression, Chk1 and Chk2 activation and leads to increased growth inhibition and death in A2780 ovarian cancer cells
2017 |
Faculty of Medicine in Hradec Králové
publication
Distinct cellular responses to replication stress leading to apoptosis or senescence
2019 |
Faculty of Medicine in Hradec Králové
publication
Replication and ribosomal stress induced by targeting pyrimidine synthesis and cellular checkpoints suppress p53-deficient tumors
2020 |
Faculty of Science
publication
Clinical Candidates Targeting the ATR-CHK1-WEE1 Axis in Cancer
2021 |
Publication without faculty affiliation
publication
Targeting the Checkpoint to Kill Cancer Cells
2015 |
Faculty of Science
publication
CHK1-CDC25A-CDK1 regulate cell cycle progression and protect genome integrity in early mouse embryos
2023 |
Faculty of Science, Central Library of Charles University
publication
The effect of ATM kinase inhibition on the initial response of human dental pulp and periodontal ligament mesenchymal stem cells to ionizing radiation
2013 |
Faculty of Medicine in Hradec Králové
publication
Comparison of the Radiosensitizing Effect of ATR, ATM and DNA-PK Kinase Inhibitors on Cervical Carcinoma Cells
2016 |
Faculty of Medicine in Hradec Králové
publication
DNA Damage Signaling in Human Skin Cells Exposed to Hexavalent Chromium
+1
2009 |
Faculty of Medicine in Hradec Králové
publication
DNA Damage Signaling in Human Skin Cells Exposed to Hexavalent Chromium
2009 |
First Faculty of Medicine
publication
Vanadocene complexes bearing N,N'-chelating ligands: Synthesis, structures and in vitro cytotoxic studies on the A549 lung adenocarcinoma cell line
2019 |
Faculty of Medicine in Hradec Králové, Faculty of Science
publication
Benfluron Induces Cell Cycle Arrest, Apoptosis and Activation of p53 Pathway in MOLT-4 Leukemic Cells
2015 |
Faculty of Medicine in Hradec Králové
publication
Bersavine: A Novel Bisbenzylisoquinoline Alkaloid with Cytotoxic, Antiproliferative and Apoptosis-Inducing Effects on Human Leukemic Cells
2020 |
Faculty of Medicine in Hradec Králové
publication
Scoulerine affects microtubule structure, inhibits proliferation, arrests cell cycle and thus culminates in the apoptotic death of cancer cells
2018 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Changes in the response of MCF-7 cells to ionizing radiation after the combination of ATM and DNA-PK inhibition
2015 |
Faculty of Medicine in Hradec Králové
publication
Antiproliferative activity and apoptosis-inducing mechanism of Amaryllidaceae alkaloid montanine on A549 and MOLT-4 human cancer cells
2023 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
The effect of Amaryllidaceae alkaloids haemanthamine and haemanthidine on cell cycle progression and apoptosis in p53-negative human leukemic Jurkat cells
2014 |
Faculty of Medicine in Hradec Králové
publication
Comparative cytotoxicity of chelidonine and homochelidonine, the dimethoxy analogues isolated from Chelidonium majus L. (Papaveraceae), against human leukemic and lung carcinoma cells
2016 |
Faculty of Medicine in Hradec Králové
publication
Identification of inhibitors for the transmembrane Trypanosoma cruzi eIF2α kinase relevant for parasite proliferation
2023 |
Faculty of Science