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Cytochrome P450 3A4
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A Double Transgenic Mouse Model Expressing Human Pregnane X Receptor and Cytochrome P450 3A4
2008 |
First Faculty of Medicine
publication
Effectiveness of human cytochrome P450 3A4 present in liposomal and microsomal nanoparticles in formation of covalent DNA adducts by ellipticine
2016 |
Faculty of Science, Second Faculty of Medicine
publication
Flexibility and stability of cytochromes P450 3A4 and BM-3
2000 |
Faculty of Science
publication
Flexibility and stability of cytochromes P450 3A4 and BM-3
2000 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
Cytochrome b(5) plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine
2017 |
Faculty of Science, Second Faculty of Medicine
publication
Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation
2019 |
Faculty of Science, Second Faculty of Medicine
publication
Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver
2019 |
Faculty of Pharmacy in Hradec Králové, Third Faculty of Medicine
publication
The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
A feasibility study of the toxic responses of human induced pluripotent stem cell-derived hepatocytes to phytochemicals
2018 |
Faculty of Pharmacy in Hradec Králové
publication
Influence of diet supplementation with green tea extract on drug-metabolizing enzymes in a mouse model of monosodium glutamate-induced obesity
2016 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Tazemetostat synergistically combats multidrug resistance by the unique triple inhibition of ABCB1, ABCC1, and ABCG2 efflux transporters in vitro and ex vivo
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové