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Cytochrome P450 oxidoreductase
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Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b5
2014 |
Faculty of Science, Second Faculty of Medicine
publication
Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b(5)
2014 |
Faculty of Science, Second Faculty of Medicine
publication
Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency
2011 |
First Faculty of Medicine
publication
Diminished FAD-binding specificity in human cytochrome P450 oxidoreductase associated with Antley-Bixler syndrome
Publication without faculty affiliation
publication
Diminished FAD-binding in human cytochrome P450 oxidoreductase associated with Antley-Bixler syndrome mutant Y459H and V492E
Publication without faculty affiliation
publication
Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of "luminal" muscle-invasive bladder cancers
2018 |
Faculty of Science
publication
Crystal structure of the FAD/NADPH-binding domain of rat neuronal nitric-oxide synthase - comparisons with NADPH-cytochrome P450 oxidoreductase
2001 |
First Faculty of Medicine
publication
The Anticancer Drug Ellipticine Induces Cytochromes P450 1A1, 1A2 and 3A, Cytochrome b(5) and NADPH:Cytochrome P450 Oxidoreductase in Rat Liver, Kidney and Lung
2013 |
Faculty of Science
publication
Cytochronne b(5) and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions
2014 |
Faculty of Science, Central Library of Charles University
publication
Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype
2016 |
First Faculty of Medicine
publication
Genetic variations in NADPH-CYP450 oxidoreductase in a Czech Slavic cohort
2015 |
First Faculty of Medicine
publication
Exposure to benzo[a]pyrene of Hepatic Cytochrome P450 Reductase Null (HRN) and P450 Reductase Conditional Null (RCN) mice: Detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and P-32-postlabelling
2012 |
Faculty of Science
publication
Studies with the hepatic NADPH:cytochrome P450 reductase null mouse reveal the role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine
2007 |
Faculty of Science
publication
Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by P-32-postlabeling
2018 |
Faculty of Science
publication
The Role of Cytochrome P450 Enzymes in Carcinogen Metabolism: Lessons Learned From Studies With Benzo[a]pyrene and Aristolochic Acid
2018 |
Faculty of Science
publication
Mutations of human cytochrome P450 reductase differentially modulate heme oxygenase-1 activity and oligomerization
2011 |
First Faculty of Medicine
publication
Effect of Hepatic Cytochrome P450 (P450) Oxidoreductase Deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine- DNA Adduct Formation in P450 Reductase Conditional Null Mice
2011 |
Faculty of Science
publication
Quercetin Induces Hepatic Lipid Omega-Oxidation and Lowers Serum Lipid Levels in Mice
2013 |
First Faculty of Medicine
publication
The Hepatic Reductase Null (HRN (TM)) and Reductase Conditional Null (RCN) mouse models as suitable tools to study metabolism, toxicity and carcinogenicity of environmental pollutants
2015 |
Faculty of Science
publication
Cytochrome b(5) impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b(5)/P450 reductase null (HBRN) mice
2018 |
Faculty of Science
publication
Application of hepatic cytochrome b(5)/P450 reductase null (HBRN) mice to study the role of cytochrome b(5) in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
2019 |
Faculty of Science