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Drug-drug interaction
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publication
Drug-drug interactions with statins: will pitavastatin overcome the statins' Achilles' heel?
2011 |
First Faculty of Medicine
publication
Entecavir Interacts with Influx Transporters hOAT1, hCNT2, hCNT3, but Not with hOCT2: The Potential for Renal Transporter-Mediated Cytotoxicity and Drug-Drug Interactions
2016 |
Faculty of Pharmacy in Hradec Králové
publication
MDR1 and BCRP Transporter-Mediated Drug-Drug Interaction between Rilpivirine and Abacavir and Effect on Intestinal Absorption
2017 |
Faculty of Pharmacy in Hradec Králové
publication
Potentially clinically significant drug-drug interactions in older patients admitted to the hospital: A cross-sectional study
2023 |
Faculty of Pharmacy in Hradec Králové
publication
Brivanib Exhibits Potential for Pharmacokinetic Drug-Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes
2019 |
Faculty of Pharmacy in Hradec Králové
publication
Impact of drug-drug interactions on phenobarbital pharmacokinetics in pediatric patients
2019 |
First Faculty of Medicine
publication
Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Paliperidon, a Second - generation Antipsychotic: Efficacy, Tolarability, and Drug-Drug Interactions
2007 |
Third Faculty of Medicine
publication
Evaluation of drug-drug interactions at the level of hepatic excretion
Publication without faculty affiliation
publication
The pregnane X receptor gene-humanized mouse: A model for investigating drug-drug interactions mediated by cytochromes P450 3A
2007 |
First Faculty of Medicine
publication
The pregnane X receptor gene-humanized mouse: A model for investigating drug-drug interactions mediated by cytochromes P450 3A
2007 |
Faculty of Physical Education and Sport
publication
Retrospective evaluation of an observational cohort by the Central and Eastern Europe Network Group shows a high frequency of potential drug-drug interactions among HIV-positive patients receiving treatment for coronavirus disease 2019 (COVID-19)
2022 |
First Faculty of Medicine, Faculty of Medicine in Pilsen
publication
Drug interactions with statins and their clinical severity and management
2011 |
Faculty of Pharmacy in Hradec Králové
publication
Renal handling of amphotericin B and amphotericin B-deoxycholate and potential renal drug-drug interactions with selected antivirals
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Ribociclib shows potential for pharmacokinetic drug-drug interactions being a substrate of ABCB1 and potent inhibitor of ABCB1, ABCG2 and CYP450 isoforms in vitro
2018 |
Faculty of Pharmacy in Hradec Králové
publication
Antiepileptic drug interactions: A clinical case demonstration
2011 |
Second Faculty of Medicine
publication
Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity
2017 |
Faculty of Pharmacy in Hradec Králové
publication
Multidrug and toxin extrusion proteins (MATE/SLC47); role in pharmacokinetics
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Tepotinib Inhibits Several Drug Efflux Transporters and Biotransformation Enzymes: The Role in Drug-Drug Interactions and Targeting Cytostatic Resistance In Vitro and Ex Vivo
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo
2015 |
Faculty of Pharmacy in Hradec Králové
publication
Olomoucine II, but Not Purvalanol A, Is Transported by Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1)
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters
2017 |
Faculty of Pharmacy in Hradec Králové
publication
Ensartinib (X-396) Effectively Modulates Pharmacokinetic Resistance Mediated by ABCB1 and ABCG2 Drug Efflux Transporters and CYP3A4 Biotransformation Enzyme
2020 |
Faculty of Pharmacy in Hradec Králové
publication
The metabolism of flubendazole in human liver and cancer cell lines
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Interplay of drug transporters P-glycoprotein (MDR1), MRP1, OATP1A2 and OATP1B3 in passage of maraviroc across human placenta
2020 |
Faculty of Pharmacy in Hradec Králové
publication
Evaluation of the Potency of Anti-HIV and Anti-HCV Drugs to Inhibit P-Glycoprotein Mediated Efflux of Digoxin in Caco-2 Cell Line and Human Precision-Cut Intestinal Slices
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Universal efavirenz determination in transport study, rat placenta perfusion and placenta lysate by HPLC-UV
2017 |
Faculty of Pharmacy in Hradec Králové
publication
Dabrafenib inhibits ABCG2 and cytochrome P450 isoenzymes; potential implications for combination anticancer therapy
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Tazemetostat synergistically combats multidrug resistance by the unique triple inhibition of ABCB1, ABCC1, and ABCG2 efflux transporters in vitro and ex vivo
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Talazoparib Does Not Interact with ABCB1 Transporter or Cytochrome P450s, but Modulates Multidrug Resistance Mediated by ABCC1 and ABCG2: An in Vitro and Ex Vivo Study
2022 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové