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Ellipticine
Publication
Class
Person
Publication
Programmes
publication
Role of cytochromes P450 and peroxidases in metabolism of the anticancer drug ellipticine: additional evidence of their contribution to ellipticine activation in rat liver, lung and kidney
2010 |
Faculty of Science
publication
Cytotoxicity of and DNA adduct formation by ellipticine in human U87MG glioblastoma cancer cells
2009 |
Faculty of Science, First Faculty of Medicine, Faculty of Mathematics and Physics
publication
Oxidation of an antitumor drug ellipticine by peroxidases
2005 |
Faculty of Science
publication
Molecular mechanisms of antineoplastic action of an anticancer drug ellipticine
2006 |
Faculty of Science
publication
Mechanism of ellipticine oxidation by peroxidases and its cytotoxicity
Publication without faculty affiliation
publication
The mechanism of cytotoxicity and DNA adduct formation by the anticancer drug ellipticine in human neuroblastoma cells
2009 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Oxidation of ellipticine by human and rat cytochromes P450 correlates with its binding to DNA
2007 |
Faculty of Science
publication
Antitumor drug ellipticine inhibits the activities of rat hepatic cytochromes P450
2005 |
Faculty of Science
publication
The comparison of cytotoxicity of the anticancer drugs doxorubicin and ellipticine to human neuroblastoma cells
2008 |
Faculty of Science
publication
An electrochemical study of interaction of an anticancer alkaloid ellipticine with DNA.
2010 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Genetical changes of high-risk neuroblastoma cell line caused by cultivation with ellipticine
2008 |
Faculty of Science
publication
The effect of pH on peroxidase-mediated oxidation of and DNA adduct formation by ellipticine
2006 |
Faculty of Science
publication
The anticancer drug ellipticine is an inducer of rat NAD(P)H : Quinone oxidoreductase
2007 |
Faculty of Science
publication
Oxidation pattern of the anticancer drug ellipticine by hepatic microsomes - Similarity between human and rat systems
2006 |
Faculty of Science
publication
Formation and persistence of DNA adducts of anticancer drug ellipticine in rats
2007 |
Faculty of Science
publication
Kinetics of ellipticine oxidation by cytochromes P450 1A1 and 1A2 reconstituted with NADPH:cytochrome P450 reductase
2007 |
Faculty of Science
publication
Cytochromes P450 reconstituted with NADPH:P450 reductase mimic the activating and detoxicating metabolism of the anticancer drug ellipticine in microsomes
2006 |
Faculty of Science
publication
Comparison of the cytotoxicity of and DNA adduct formation by the anticancer drug ellipticine in human breast adenocarcinoma, leukemia and neuroblastoma cells
2007 |
Faculty of Science
publication
The study of activation and detoxication metabolism of the anticancer drug ellipticine by cytochromes P450 system in vitro and in vivo
Publication without faculty affiliation
publication
Effect of ellipticine on neuroblastoma and its affection by valproic acid - in vitro study
2005 |
Second Faculty of Medicine
publication
Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH: Cytochrome P450 reductase null mouse
2008 |
Faculty of Science
publication
Studies with the hepatic NADPH:cytochrome P450 reductase null mouse reveal the role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine
2007 |
Faculty of Science
publication
DNA adduct formation by the anticancer drug ellipticine and its hydroxy derivatives in human breast adenocarcinoma MCF-7 cells
2004 |
Faculty of Science
publication
Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2
2008 |
Faculty of Science
publication
Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine
2007 |
Faculty of Science, Central Library of Charles University, Second Faculty of Medicine
publication
The anticancer drug ellipticine is a potent inducer of rat cytochromes P450 1A1 and 1A2, thereby modulating its own metabolism
2007 |
Faculty of Science
publication
Anticancer drug ellipticine is oxidized by lactoperoxidase
2002 |
Faculty of Science
publication
Ellipticines as DNA-Targeted Chemotherapeutics
2014 |
Faculty of Science
publication
Ellipticine targeting to tumor cells
2001 |
Faculty of Science
publication
Ellipticine targeting to tumor cells
2001 |
First Faculty of Medicine, Faculty of Mathematics and Physics