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Gene reporter assay
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publication
Construction and characterization of a reporter gene cell line for assessment of human glucocorticoid receptor activation
2012 |
Faculty of Pharmacy in Hradec Králové
publication
Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver
2019 |
Faculty of Pharmacy in Hradec Králové, Third Faculty of Medicine
publication
Dexamethasone accelerates degradation of aryl hydrocarbon receptor (AHR) and suppresses CYP1A1 induction in placental JEG-3 cell line
2013 |
Faculty of Pharmacy in Hradec Králové
publication
The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator
2016 |
Faculty of Pharmacy in Hradec Králové
publication
The transcription factor GATA-4 regulates cytochrome P4502C19 gene expression
2010 |
Publication without faculty affiliation
publication
MicroRNAs mediated regulation of glutathione peroxidase 7 expression and its changes during adipogenesis
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Physical Education and Sport
publication
The role of residues T248, Y249 and T422 in the function of human pregnane X receptor
2013 |
Faculty of Pharmacy in Hradec Králové
publication
U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells
2014 |
Faculty of Pharmacy in Hradec Králové