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HI-6
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publication
Time-dependent changes in concentration of two clinically used acetylcholinesterase reactivators (HI-6 and obidoxime) in rat plasma determined by HPLC techniques after in vivo administration
2010 |
Faculty of Medicine in Hradec Králové
publication
A comparison of efficacy of the acetylcholinesterase modulators in dogs using quantitative histochemistry
2010 |
Faculty of Medicine in Hradec Králové
publication
A comparison of reactivation and therapeutic efficacy of the oxime K203 and its fluorinated analog (KR-22836) with currently available oximes (obidoxime, trimedoxime, HI-6) against tabun in rats and mice
2010 |
Faculty of Medicine in Hradec Králové
publication
A comparison of tabun-inhibited rat brain acetylcholinesterase reactivation by three oximes (HI-6, obidoxime, and K048) in vivo detected by biochemical and histochemical techniques
2010 |
Faculty of Medicine in Hradec Králové
publication
Hyaluronidase: Its effects on HI-6 dichloride and dimethanesulphonate pharmacokinetic profile in pigs
2013 |
Faculty of Medicine in Hradec Králové
publication
Could oxime HI-6 really be considered as 'broad-spectrum' antidote?
2009 |
Central Library of Charles University
publication
Entry of oxime K027 into the different parts of rat brain: Comparison with obidoxime and oxime HI-6
2014 |
Publication without faculty affiliation
publication
Impact of paraoxon followed by acetylcholinesterase reactivator HI-6 on gastric myoelectric activity in experimental pigs
2013 |
Faculty of Medicine in Hradec Králové
publication
Capability testing of well-known oximes (pralidoxime, trimedoxime, HI-6, methoxime, obidoxime) to reactivate in vitro chlorpyrifos-inhibited acetylcholinesterase
Publication without faculty affiliation
publication
HI-6 oxime (an acetylcholinesterase reactivator): blood plasma pharmacokinetics and organ distribution in experimental pigs
2014 |
Faculty of Medicine in Hradec Králové
publication
Intravenous application of HI-6 salts (dichloride and dimethansulphonate) in pigs: comparison with pharmacokinetics profile after intramuscular administration
2013 |
Faculty of Medicine in Hradec Králové
publication
HI-6 treatment does not reactivate sarin inhibited acetylcholinesterase activity in dog brain when administered in human therapeutical dose 30 minutes after the poisoning
2016 |
Faculty of Medicine in Hradec Králové
publication
The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of soman poisoning in rats and mice
2009 |
Faculty of Medicine in Hradec Králové
publication
The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of tabun poisoning in rats and mice
2010 |
Faculty of Medicine in Hradec Králové
publication
Could oxime HI-6 really be considered as 'broad-spectrum' antidote?
2009 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
publication
Twelve different HI-6 salts and their potency to reactivate cyclosarin inhibited AChE in vitro
2007 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
publication
In vitro transdermální penetrace cholinesterázového reaktivátoru HI-6
1998 |
Faculty of Pharmacy in Hradec Králové
publication
In vitro effects of acetylcholinesterase reactivators on monoamine oxidase activity
2011 |
First Faculty of Medicine
publication
A Comparison of the Neuroprotective and Reactivating Efficacy of a Novel Bispyridinium Oxime K870 with Commonly Used Pralidoxime and the Oxime HI-6 in Tabun-Poisoned Rats
2021 |
Publication without faculty affiliation
publication
The benefit of combinations of oximes for the ability of antidotal treatment to counteract sarin-induced brain damage in rats
2018 |
Publication without faculty affiliation
publication
Relationship between the structure and activity of acetylcholinesterase reactivators. Reactivation of AChE inhibited with pesticides
Publication without faculty affiliation
publication
The benefit of combinations of oximes for the reactivating and therapeutic efficacy of antidotal treatment of sarin poisoning in rats and mice
2011 |
Faculty of Medicine in Hradec Králové
publication
In vitro reactivation of erythrocytal acetylcholinesterase and plasmatic buturycholinesterase inhibited with the pesticide paraoxon
Publication without faculty affiliation
publication
In vitro effects of acetylcholinesterase reactivators on monoamine oxidase activity
2011 |
Faculty of Physical Education and Sport, First Faculty of Medicine
publication
Acetylcholinesterase reactivators (HI-6, obidoxime, trimedoxime, K027, K075, K127, K203, K282): structural evaluation of human serum albumin binding and absorption Kinetics
2013 |
Publication without faculty affiliation
publication
Synthesis of series of new acetlcholineesterase reactivators bearing but-2-ine linker and their in vitro evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase
Publication without faculty affiliation
publication
Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro
2008 |
Central Library of Charles University
publication
Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker - Preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase
2007 |
Publication without faculty affiliation
publication
A comparison of the reactivating and therapeutic efficacy of chosen combinations of oximes with individual oximes against VX in rats and mice
2011 |
Faculty of Medicine in Hradec Králové
publication
The ability of oxime mixtures to increase the reactivating and therapeutic efficacy of antidotal treatment of cyclosarin poisoning in rats and mice
2012 |
Faculty of Medicine in Hradec Králové