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HRN mice
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Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2
2008 |
Faculty of Science
publication
Exposure to benzo[a]pyrene of Hepatic Cytochrome P450 Reductase Null (HRN) and P450 Reductase Conditional Null (RCN) mice: Detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and P-32-postlabelling
2012 |
Faculty of Science
publication
The effect of benzo[a]pyrene on metabolic activation of anticancer drug ellipticine in mice
2013 |
Faculty of Science
publication
Cytochronne b(5) and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions
2014 |
Faculty of Science, Central Library of Charles University
publication
Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model
2011 |
Second Faculty of Medicine
publication
Cytochrome b(5) impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b(5)/P450 reductase null (HBRN) mice
2018 |
Faculty of Science
publication
Knockout and humanized mice as suitable tools to identify enzymes metabolizing the human carcinogen aristolochic acid
2014 |
Faculty of Science
publication
Activation and detoxification metabolism of urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone by rat and mouse hepatic microsomes
2012 |
Faculty of Science
publication
Application of hepatic cytochrome b(5)/P450 reductase null (HBRN) mice to study the role of cytochrome b(5) in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
2019 |
Faculty of Science