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MAPK pathway
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publication
Mutations in the RAS/MAPK Pathway Drive Replication Repair-Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition
2021 |
Second Faculty of Medicine
publication
Soman poisoning alters p38 MAPK pathway in rat cerebellar Purkinje cells
2009 |
Faculty of Medicine in Hradec Králové, Central Library of Charles University
publication
Combination Treatment Targeting mTOR and MAPK Pathways Has Synergistic Activity in Multiple Myeloma
2023 |
First Faculty of Medicine
publication
Soman poisoning alters p38 MAPK pathway in rat cerebellar Purkinje cells
2009 |
Faculty of Medicine in Hradec Králové
publication
Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas
2020 |
Second Faculty of Medicine
publication
Investigation of Rare Non-Coding Variants in Familial Multiple Myeloma
2023 |
Faculty of Medicine in Pilsen
publication
Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Many Distinct Ways Lead to Drug Resistance in BRAF- and NRAS-Mutated Melanomas
2021 |
First Faculty of Medicine
publication
p38 MAPK is activated but does not play a key role during apoptosis induction by saturated fatty acid in human pancreatic β-cells
2016 |
Third Faculty of Medicine
publication
LOGGIC/FIREFLY-2: a phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration
2024 |
Second Faculty of Medicine
publication
Epigenetic profiling reveals a subset of pediatric-type glioneuronal tumors characterized by oncogenic gene fusions involving several targetable kinases
2022 |
Second Faculty of Medicine
publication
New trends in the multiple myeloma treatment
2019 |
First Faculty of Medicine
publication
Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas
2019 |
Second Faculty of Medicine
publication
Valproate activates ERK signaling pathway in primary human hepatocytes
2014 |
Faculty of Pharmacy in Hradec Králové
publication
A comprehensive evaluation of pathogenic mutations in primary cutaneous melanomas, including the identification of novel loss-of-function variants
2019 |
First Faculty of Medicine
publication
Mutation and phenotypic spectrum in patients with cardio-facio-cutaneous and Costello syndrome
2008 |
Second Faculty of Medicine
publication
Malignant Melanoma - from Classical Histology towards Molecular Genetic Testing
2017 |
Faculty of Medicine in Hradec Králové, First Faculty of Medicine, Second Faculty of Medicine
publication
Neurofibromatosis von Recklinghausen type 1 (NF1) - clinical picture and molecular-genetics diagnostic
2015 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Genotype and phenotype in patients with Noonan syndrome and a RIT1 mutation
2016 |
Second Faculty of Medicine
publication
Combined immunotherapy improves outcome for replication repair deficient (RRD) high-grade glioma failing anti-PD1 monotherapy: A report from the International RRD Consortium
2024 |
Second Faculty of Medicine
publication
Molecular Targets for Cancer Therapy in the PI3K/AKT/mTOR Pathway
2014 |
Faculty of Medicine in Pilsen
publication
Three Fusarium oxysporum mitogen-activated protein kinases (MAPKs) have distinct and complementary roles in stress adaptation and cross-kingdom pathogenicity
2017 |
Faculty of Science
publication
Intragenic NF1 deletions in sinonasal mucosal malignant melanoma
2022 |
Faculty of Medicine in Hradec Králové
publication
A Complex Role for FGF-2 in Self-Renewal, Survival, and Adhesion of Human Embryonic Stem Cells
2009 |
First Faculty of Medicine, Faculty of Physical Education and Sport
publication
An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia
2017 |
First Faculty of Medicine, Second Faculty of Medicine
publication
An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia
2017 |
Central Library of Charles University
publication
The response of human ectomesenchymal dental pulp stem cells to cisplatin treatment
2012 |
Faculty of Medicine in Hradec Králové
publication
The requirements for dasatinib sensitivity in human melanoma cell lines
2014 |
First Faculty of Medicine
publication
Clinicogenomic associations in childhood Langerhans cell histiocytosis: an international cohort study
2023 |
Second Faculty of Medicine
publication
The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas
2020 |
Second Faculty of Medicine