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MEK/ERK
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The MEK-ERK-MST1 Axis Potentiates the Activation of the Extrinsic Apoptotic Pathway during GDC-0941 Treatment in Jurkat T Cells
2019 |
Central Library of Charles University, Faculty of Science
publication
The requirements for dasatinib sensitivity in human melanoma cell lines
2014 |
First Faculty of Medicine
publication
Regorafenib monotherapy in pretreated metastatic colorectal cancer (CORRECT): an international, multicenter, randomized, placebo-controlled clinical trial Phase 3
2013 |
Second Faculty of Medicine
publication
RNA-sequencing of myxoinflammatory fibroblastic sarcomas reveals a novel SND1::BRAF fusion and 3 different molecular aberrations with the potential to upregulate the TEAD1 gene including SEC23IP::VGLL3 and TEAD1::MRTFB gene fusions
2022 |
Faculty of Medicine in Pilsen
publication
Either IL-7 activation of JAK-STAT or BEZ inhibition of PI3K-AKT-mTOR pathways dominates the single-cell phosphosignature of ex vivo treated pediatric T-cell acute lymphoblastic leukemia cells
2022 |
Second Faculty of Medicine
publication
Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia
2010 |
Second Faculty of Medicine
publication
Valproate activates ERK signaling pathway in primary human hepatocytes
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Loss-of-function of ENT3 drives histiocytosis and inflammation through TLR-MAPK signaling
2023 |
Second Faculty of Medicine
publication
Many Distinct Ways Lead to Drug Resistance in BRAF- and NRAS-Mutated Melanomas
2021 |
First Faculty of Medicine
publication
The peripheral cannabinoid receptor Cb2, frequently expressed on AML blasts, either induces a neutrophilic differentiation block or confers abnormal migration properties in a ligand-dependent manner
2004 |
Central Library of Charles University
publication
U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Interferon-regulated suprabasin is essential for stress-induced stem-like cell conversion and therapy resistance of human malignancies
2019 |
Central Library of Charles University
publication
Interferon-regulated suprabasin is essential for stress-induced stem-like cell conversion and therapy resistance of human malignancies
2019 |
First Faculty of Medicine, Faculty of Medicine in Pilsen, Central Library of Charles University, Third Faculty of Medicine
publication
Langerhans Cell Histiocytosis Associated With Renal Cell Carcinoma Is a Neoplastic Process Clinicopathologic and Molecular Study of 7 Cases
2020 |
Faculty of Medicine in Pilsen