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NAD(P)H quinone:oxidoreductase
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publication
The anticancer drug ellipticine is an inducer of rat NAD(P)H : Quinone oxidoreductase
2007 |
Faculty of Science
publication
The environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols
2005 |
Faculty of Science
publication
Dicoumarol inhibits rat NAD(P)H:quinone oxidoreductase in vitro and induces its expression in vivo
2014 |
Faculty of Science
publication
The Human Carcinogen Aristolochic Acid I Is Activated to Form DNA Adducts by Human NAD(P)H:quinone Oxidoreductase Without the Contribution of Acetyltransferases or Sulfotransferases
2011 |
Second Faculty of Medicine
publication
The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity
2008 |
Faculty of Science
publication
Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase
2003 |
Faculty of Science
publication
The Human Carcinogen Aristolochic Acid I Is Activated to Form DNA Adducts by Human NAD(P)H:quinone Oxidoreductase Without the Contribution of Acetyltransferases or Sulfotransferases
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
The effect of aristolochic acid I on expression of NAD(P)H:quinone oxidoreductase in mice and rats-A comparative study
2014 |
Faculty of Science
publication
The environmental pollutant and carcinogen 3-nitrobenzanthrone and its human metabolite 3-aminobenzanthrone are potent inducers of rat hepatic cytochromes P450 1A1 and-1A2 and NAD(P) H : quinone oxidoreductase
2006 |
Faculty of Science
publication
Induced Expression of Cytochrome P450 1A and NAD(P)H:Quinone Oxidoreductase Determined at mRNA, Protein, and Enzyme Activity Levels in Rats Exposed to the Carcinogenic Azo Dye 1-Phenylazo-2-naphthol (Sudan I)
2013 |
Faculty of Science
publication
Cranberry extract-enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice
2015 |
Faculty of Pharmacy in Hradec Králové
publication
NAD(P)H:quinone oxidoreductase expression in Cyp1a-knockout and CYP1A-humanized mouse lines and its effect on bioactivation of the carcinogen aristolochic acid I
2012 |
Faculty of Science
publication
Association of superoxide dismutases and NAD(P)H quinone oxidoreductases with prognosis of patients with breast carcinomas
2012 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Reductive activation of environmental pollutants 3-nitrobenzanthrone and 2-nitrobenzanthrone
2007 |
Faculty of Science
publication
NAD(P)H:quinone oxidoreductase 1 Pro187Ser polymorphism and expression do not cosegregate with clinico-pathological characteristcs of human mammary tumors
2009 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue
2021 |
Faculty of Science, Central Library of Charles University
publication
Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases
2011 |
Faculty of Science
publication
Mechanisms of Enzyme-Catalyzed Reduction of Two Carcinogenic Nitro-Aromatics, 3-Nitrobenzanthrone and Aristolochic Acid I: Experimental and Theoretical Approaches
2014 |
Faculty of Science
publication
Sulforaphane Alters beta-Naphthoflavone-Induced Changes in Activity and Expression of Drug-Metabolizing Enzymes in Rat Hepatocytes
2017 |
Faculty of Pharmacy in Hradec Králové
publication
A role of biotransformation enzymes in the Development of renal injury and urothelial cancer caused by aristolochic acid: Urgent questions difficult answers
2009 |
Faculty of Science
publication
Knockout and humanized mice as suitable tools to identify enzymes metabolizing the human carcinogen aristolochic acid
2014 |
Faculty of Science
publication
Molecular dynamics comparison of E. coli WrbA apoprotein and holoprotein
2014 |
Faculty of Science
publication
The influence of dicoumarol on the bioactivation of the carcinogen aristolochic acid I in rats
2014 |
Faculty of Science
publication
Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats
2011 |
Faculty of Science
publication
Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats
2021 |
Faculty of Science
publication
Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy
2008 |
Faculty of Science
publication
Low Expression of NQO1 Predicts Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Cancer Patients treated with TAC Regimen
2012 |
Faculty of Medicine in Hradec Králové
publication
Association between exposure-relevant polymorphisms in CYP1B1,EPHX1,NQ01,GSTM1,GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population
2010 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Induction of xenobiotic-metabolizing enzymes in hepatocytes by beta-naphthoflavone: Time-dependent changes in activities, protein and mRNA levels
2018 |
Faculty of Pharmacy in Hradec Králové
publication
Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by P-32-postlabeling
2018 |
Faculty of Science