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NADPH:CYP reductase
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Reductive activation of environmental pollutants 3-nitrobenzanthrone and 2-nitrobenzanthrone
2007 |
Faculty of Science
publication
Cancerogenic and nephrotoxic aristolochic acids are activated by human cytochromes P450 1A1 and 1A: study on enzyme-aristolochic acid molecular interactions
2002 |
Faculty of Science
publication
Kinetics of ellipticine oxidation by cytochromes P450 1A1 and 1A2 reconstituted with NADPH:cytochrome P450 reductase
2007 |
Faculty of Science
publication
Evidence for reductive activation of carcinogenic aristolochic acid by CYP1A1 and CYP1A2 enzymes: 32P-postlabelling analysis of DNA adduct formation
1999 |
Faculty of Science
publication
The binding affinity of carcinogenic N-nitrosodimethylamine and N-nitrosomethylaniline to cytochromes P450 2B4, 2E1 and 3A6 does not dictate the rate of their enzymatic N- demethylation.
2010 |
Faculty of Science
publication
A role of biotransformation enzymes in the Development of renal injury and urothelial cancer caused by aristolochic acid: Urgent questions difficult answers
2009 |
Faculty of Science
publication
Human cytochrome-P450 enzymes metabolize N-(2-methoxyphenyl)hydroxylamine, a metabolite of the carcinogens o-anisidine and o-nitroanisole, thereby dictating its genotoxicity
2011 |
Faculty of Science
publication
The effect of benzo[a]pyrene on metabolic activation of anticancer drug ellipticine in mice
2013 |
Faculty of Science
publication
Activation and detoxification metabolism of urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone by rat and mouse hepatic microsomes
2012 |
Faculty of Science
publication
Oxidation of carcinogenic benzo[a]pyrene by human and rat cytochrome P450 1A1 and its influencing by cytochrome b5 - a comparative study
2013 |
Faculty of Science
publication
Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine
2016 |
Faculty of Science
publication
Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver
2011 |
Second Faculty of Medicine