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Obidoxime
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publication
Time-dependent changes in concentration of two clinically used acetylcholinesterase reactivators (HI-6 and obidoxime) in rat plasma determined by HPLC techniques after in vivo administration
2010 |
Faculty of Medicine in Hradec Králové
publication
A comparison of reactivation and therapeutic efficacy of the oxime K203 and its fluorinated analog (KR-22836) with currently available oximes (obidoxime, trimedoxime, HI-6) against tabun in rats and mice
2010 |
Faculty of Medicine in Hradec Králové
publication
A comparison of tabun-inhibited rat brain acetylcholinesterase reactivation by three oximes (HI-6, obidoxime, and K048) in vivo detected by biochemical and histochemical techniques
2010 |
Faculty of Medicine in Hradec Králové
publication
Influence of obidoxim, reactivator of acetylcholinesterase, on the process of human platelet aggregation in vitro
2005 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
publication
Entry of oxime K027 into the different parts of rat brain: Comparison with obidoxime and oxime HI-6
2014 |
Publication without faculty affiliation
publication
Capability testing of well-known oximes (pralidoxime, trimedoxime, HI-6, methoxime, obidoxime) to reactivate in vitro chlorpyrifos-inhibited acetylcholinesterase
Publication without faculty affiliation
publication
The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of tabun poisoning in rats and mice
2010 |
Faculty of Medicine in Hradec Králové
publication
In vitro effects of acetylcholinesterase reactivators on monoamine oxidase activity
2011 |
First Faculty of Medicine
publication
Comparison of plasma and brain exposure levels of bis-pyridinium oximes KR-22839 and KR-26256 with asoxime and obidoxime in mice
2019 |
Publication without faculty affiliation
publication
Relationship between the structure and activity of acetylcholinesterase reactivators. Reactivation of AChE inhibited with cyclosarine
Publication without faculty affiliation
publication
Relationship between the structure and activity of acetylcholinesterase reactivators. Reactivation of AChE inhibited with pesticides
Publication without faculty affiliation
publication
In vitro reactivation of erythrocytal acetylcholinesterase and plasmatic buturycholinesterase inhibited with the pesticide paraoxon
Publication without faculty affiliation
publication
In vitro effects of acetylcholinesterase reactivators on monoamine oxidase activity
2011 |
Faculty of Physical Education and Sport, First Faculty of Medicine
publication
Acetylcholinesterase reactivators (HI-6, obidoxime, trimedoxime, K027, K075, K127, K203, K282): structural evaluation of human serum albumin binding and absorption Kinetics
2013 |
Publication without faculty affiliation
publication
Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro
2008 |
Central Library of Charles University
publication
Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker - Preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase
2007 |
Publication without faculty affiliation
publication
A comparison of the reactivating and therapeutic efficacy of newly developed bispyridinium oximes (K250, K251) with commonly used oximes against tabun in rats and mice
2009 |
Central Library of Charles University
publication
Reactivation of Human Acetylcholinesterase and Butyrylcholinesterase Inhibited by Leptophos-Oxon with Different Oxime Reactivators in Vitro
2010 |
Publication without faculty affiliation
publication
Countermeasures in organophosphorus intoxication: pitfalls and prospects
2022 |
Publication without faculty affiliation
publication
Pyridinium oximes with ortho-positioned chlorine moiety exhibit improved physicochemical properties and efficient reactivation of human Acetylcholinesterase inhibited by several nerve agents
2018 |
Publication without faculty affiliation
publication
Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators
2020 |
Publication without faculty affiliation
publication
In vitro functional interactions of acetylcholine esterase inhibitors and muscarinic receptor antagonists in the urinary bladder of the rat
2014 |
Faculty of Pharmacy in Hradec Králové
publication
In Vitro Ability of Currently Available Oximes to Reactivate Organophosphate Pesticide-Inhibited Human Acetylcholinesterase and Butyrylcholinesterase
2011 |
Publication without faculty affiliation
publication
A comparison of the efficiacy of new asymmetric bispyridinium oximes (K027, K048) with currently available oximes against tabun by in vivo methods
2006 |
Faculty of Pharmacy in Hradec Králové
publication
Russian VX: Inhibition and reactivation of acetylcholinesterase compared with VX agent
2006 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
publication
Oxidative stress status assessment of rats' brains injury following subacute exposure to K-oximes
2023 |
Publication without faculty affiliation
publication
Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro
2008 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
publication
Monooxime bispyridinium reactivators bearing xylene linker synthesis and in vitro evaluation on model of organophosphate-inhibited acetylcholinesterase
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker - Preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase
2007 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
publication
In vitro screening of oxime reactivators on the model of paraoxon-inhibited acetylcholinesterase - SAR study
2010 |
Central Library of Charles University