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TKI resistance
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publication
Somatic Mutations in Oncogenes Are in Chronic Myeloid Leukemia Acquired De Novo via Deregulated Base-Excision Repair and Alternative Non-Homologous End Joining
2021 |
First Faculty of Medicine, Second Faculty of Medicine, Faculty of Physical Education and Sport
publication
An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia
2017 |
First Faculty of Medicine, Second Faculty of Medicine
publication
An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia
2017 |
Central Library of Charles University
publication
Patient with three EGFR mutations - gradual development of resistance to previous targeted treatment
2018 |
Faculty of Science, Faculty of Medicine in Pilsen
publication
Next-generation deep sequencing improves detection of BCR-ABL1 kinase domain mutations emerging under tyrosine kinase inhibitor treatment of chronic myeloid leukemia patients in chronic phase
2015 |
First Faculty of Medicine
publication
Proteomic analysis of imatinib-resistant CML-T1 cells reveals calcium homeostasis as a potential therapeutic target
2016 |
First Faculty of Medicine, Faculty of Science
publication
Sensitive detection methods are key to identify secondary EGFR c.2369C>T p.(Thr790Met) in non-small cell lung cancer tissue samples
2020 |
Faculty of Medicine in Hradec Králové