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Tacrine
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publication
Tacrine and its derivatives in the therapy of Alzheimer's disease
2012 |
Publication without faculty affiliation
publication
A Resurrection of 7-MEOTA: A Comparison with Tacrine
2013 |
Faculty of Pharmacy in Hradec Králové
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Pro-cognitive effect of bis(7)-tacrine as potential therapeutic agent against neurodegenerative disorders
2018 |
Publication without faculty affiliation
publication
The pharmacology of tacrine at N-methyl-D-aspartate receptors
2017 |
Publication without faculty affiliation
publication
Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors
2015 |
Publication without faculty affiliation
publication
Intracellular distribution of new tacrine analogues as a potential cause of their cytotoxicity against human neuroblastoma cells SH-SY5Y
2018 |
Publication without faculty affiliation
publication
Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation
2023 |
Faculty of Pharmacy in Hradec Králové
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Novel tacrine/acridine anticholinesterase inhibitors with piperazine and thiourea linkers
2014 |
Faculty of Pharmacy in Hradec Králové
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Conjugates on the basis of tacrine and tryptophan, a method of their preparation and their use
Publication without faculty affiliation
publication
Multifunctional properties of novel tacrine congeners: cholinesterase inhibition and cytotoxic activity
2018 |
Publication without faculty affiliation
publication
N-alkylated tacrine derivatives as potential agents in Alzheimer's disease therapy
2019 |
Faculty of Medicine in Hradec Králové
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Synthesis and in vitro evaluation of new tacrine derivatives - bis-alkylene linked 7-MEOTA
2010 |
Central Library of Charles University
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Exploring structure-activity relationship in tacrine-squaramide derivatives as potent Cholinesterase inhibitors
2019 |
Publication without faculty affiliation
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Impact of tacrine and 7-methoxytacrine on gastric myoelectrical activity assessed using electrogastrography in experimental pigs
2015 |
Faculty of Medicine in Hradec Králové
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In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers
2019 |
Publication without faculty affiliation
publication
Multitarget tacrine hybrids with neuroprotective properties to confront Alzheimer's disease
2017 |
Publication without faculty affiliation
publication
Design and synthesis of novel tacrine-indole hybrids as potential multitarget-directed ligands for the treatment of Alzheimer's disease
2021 |
Publication without faculty affiliation
publication
Supporting the integration of mathematical, reading and language literacy in primary school pupils - TAČR project
2023 |
Faculty of Education
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Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease
2021 |
Publication without faculty affiliation
publication
Synthesis and Biological Evaluation of Novel Tacrine Derivatives and Tacrine-Coumarin Hybrids as Cholinesterase Inhibitors
2014 |
Publication without faculty affiliation
publication
Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-D-Aspartate receptors
2021 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové, Faculty of Science
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Tacrine-Coumarin Derivatives as Topoisomerase Inhibitors with Antitumor Effects on A549 Human Lung Carcinoma Cancer Cell Lines
2021 |
Publication without faculty affiliation
publication
Tacrine and its 7-methoxy derivate; time-change concentration in plasma and brain tissue and basic toxicological profile in rats
2021 |
Faculty of Medicine in Hradec Králové
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UHPLC-Orbitrap study of the first phase tacrine in vitro metabolites and related Alzheimer's drug candidates using human liver microsomes
2023 |
Faculty of Pharmacy in Hradec Králové
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Varied word problems
2022 |
Faculty of Education
publication
Tacrine - Benzothiazoles: Novel class of potential multitarget anti-Alzheimer's drugs dealing with cholinergic, amyloid and mitochondrial systems
2021 |
Central Library of Charles University, Faculty of Medicine in Hradec Králové
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Tacrine and muscarinic receptors: Unusual mechanism of interaction.
Publication without faculty affiliation
publication
The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease
2018 |
Faculty of Pharmacy in Hradec Králové
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Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease
2019 |
Central Library of Charles University, Faculty of Medicine in Hradec Králové
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Multitarget Drug Design Strategy: Quinone-Tacrine Hybrids Designed To Block Amyloid-beta Aggregation and To Exert Anticholinesterase and Antioxidant Effects
2014 |
Publication without faculty affiliation