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benzo[a] pyrene
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Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method
2009 |
Faculty of Science
publication
Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2
2008 |
Faculty of Science
publication
Effect of benzo[a]pyrene treatment on hepatic cytochrrome P450 and NADPH: cytochrrome P450 reductase (POR) levels in mice with liver-specific deletion of the POR gene
2007 |
Faculty of Science
publication
Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice
2008 |
Faculty of Science
publication
The effect of Polycyclic aromatic hydrocarbons to bone marrow
2004 |
Faculty of Medicine in Hradec Králové
publication
The effect of benzo[a]pyrene on metabolic activation of anticancer drug ellipticine in mice
2013 |
Faculty of Science
publication
The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers
2016 |
Faculty of Science
publication
Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes
2021 |
Faculty of Science
publication
Oxidation of carcinogenic benzo[a]pyrene by human and rat cytochrome P450 1A1 and its influencing by cytochrome b5 - a comparative study
2013 |
Faculty of Science
publication
The relationship between DNA adduct formation by benzo[a]pyrene and expression of its activation enzyme cytochrome P450 1A1 in rat
2013 |
Faculty of Science
publication
Exposure of rats to exogenous endocrine disruptors 17alpha-ethinylestradiol and benzo(a)pyrene and an estrogenic hormone estradiol induces expression of cytochromes P450 involved in their metabolism
2016 |
Faculty of Science
publication
Exposure to endocrine disruptors 17alpha-ethinylestradiol and estradiol influences cytochrome P450 1A1-mediated genotoxicity of benzo[a]pyrene and expression of this enzyme in rats
2018 |
Faculty of Science
publication
Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene
2015 |
Faculty of Science
publication
The Role of Cytochrome P450 Enzymes in Carcinogen Metabolism: Lessons Learned From Studies With Benzo[a]pyrene and Aristolochic Acid
2018 |
Faculty of Science
publication
The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo [a] pyrene: Effects in human colorectal HCT116 TP53( / ), TP53( /-) and TP53(-/-) cells
2018 |
Faculty of Science
publication
The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice
2016 |
Faculty of Science
publication
Genetic polymorphisms in biotransformation enzymes for benzo[a]pyrene and related levels of benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA adducts in Goeckerman therapy
2016 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Exposure to benzo[a]pyrene of Hepatic Cytochrome P450 Reductase Null (HRN) and P450 Reductase Conditional Null (RCN) mice: Detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and P-32-postlabelling
2012 |
Faculty of Science
publication
Effect of dihydromyricetin on benzo[a]pyrene activation in rats
2014 |
Faculty of Science, Faculty of Pharmacy in Hradec Králové
publication
Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b5
2014 |
Faculty of Science, Second Faculty of Medicine
publication
Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b(5)
2014 |
Faculty of Science, Second Faculty of Medicine
publication
Cytochronne b(5) and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions
2014 |
Faculty of Science, Central Library of Charles University
publication
Influence of immunization with non-genotoxic PAH-KLH conjugates on the resistance of organisms exposed to benzo(a)pyrene
2012 |
Second Faculty of Medicine, Third Faculty of Medicine
publication
Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems
2017 |
Faculty of Science
publication
Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine
2016 |
Faculty of Science
publication
Benzo(a)pyrene-albumin adducts in humans exposed to polycyclic aromatic hydrocarbons in an industrial area of Poland
1997 |
Faculty of Medicine in Hradec Králové
publication
Induced expression of microsomal cytochrome b(5) determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I)
2016 |
Faculty of Science
publication
NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1
2016 |
Faculty of Science
publication
Micronuclei levels in mothers and their newborns from regions with different types of air pollution
2011 |
Second Faculty of Medicine, Central Library of Charles University
publication
NADH:Cytochrome b(5) Reductase and Cytochrome b(5) Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene
2016 |
Faculty of Science