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carbonyl reduction
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Aldo-keto reductases (AKR) from the AKR1C subfamily catalyze the carbonyl reduction of the novel anticancer drug oracin in man
2007 |
Publication without faculty affiliation
publication
Carbonyl Reduction of Flubendazole in the Human Liver: Strict Stereospecificity, Sex Difference, Low Risk of Drug Interactions
2019 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Carbonyl reduction pathways in drug metabolism
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Enantioselectivity in the carbonyl reduction of anthelmintic flubendazole in pig and pheasant
Publication without faculty affiliation
publication
Comparison of in vitro carbonyl reduction of benfluron and dimefluron
2000 |
Faculty of Pharmacy in Hradec Králové
publication
Aldo-keto reductases (AKR) from the AKR1C subfamily catalyze the carbonyl reduction of the novel anticancer drug oracin in man
2007 |
Faculty of Pharmacy in Hradec Králové
publication
Use of chiral liquid chromatography for the evaluation of stereospecificity in the carbonyl reduction of potential benzo[c]fluorene antineoplastics benfluron and dimefluron in various species
2005 |
Faculty of Pharmacy in Hradec Králové
publication
Comparison of Benfluron and Dimefluron Carbonyl Reduction in Rat Microsomes and Cytosol
2000 |
Faculty of Pharmacy in Hradec Králové
publication
Carbonyl reduction of warfarin: Identification and characterization of human warfarin reductases
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Carbonyl reduction of the potential cytostatic drugs benfluron and 3,9-dimethoxybenfluron in human in vitro
2002 |
Publication without faculty affiliation
publication
Purification and characterization of AKR1B10 from human liver: role in carbonyl reduction of xenobiotics
2006 |
Faculty of Pharmacy in Hradec Králové
publication
Use of chiral reversed-phase liquid chromatography for the evaluation of stereoselectivity in the carbonyl reduction of potential benzo[c]fluorene antineoplastics benfluron and dimefluron in various species
Publication without faculty affiliation
publication
In vivo effect of oracin on doxorubicin reduction, biodistribution and efficacy in Ehrlich tumor bearing mice
2013 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Purification and characterization of an oxidoreductase in human liver cytosol participating in carbonyl reduction of the tobacco-specific nitrosamine NNK
Publication without faculty affiliation
publication
The novel anticancer drug oracin: different stereospecificity and cooperativity for carbonyl reduction by purified human liver 11beta-hydroxysteroid dehydrogenase type 1
2004 |
Faculty of Pharmacy in Hradec Králové
publication
Stereochemical aspects of carbonyl reduction of the original anticancer drug oracin by mouse liver microsomes and purified 11Beta-hydroxysteroid dehydrogenase type 1
2003 |
Faculty of Pharmacy in Hradec Králové
publication
Haemonchus contortus - metabolism of anthelmintics and other model xenobiotics in vitro
Publication without faculty affiliation
publication
Partial purification and characterization of new human membrane-bound carbonyl reductase playing a role in the deactivation of the anticancer drug oracin
2009 |
Central Library of Charles University
publication
Biotransformation of flubendazole and selected model xenobiotics in Haemonchus contortus
2008 |
Central Library of Charles University
publication
Inactivation of the anticancer drugs doxorubicin and oracin by aldo-keto reductase (AKR) 1C3
2008 |
Central Library of Charles University
publication
Human DHRS7, promising enzyme in metabolism of steroids and retinoids?
2016 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Reduction of doxorubicin and oracin and induction of carbonyl reductase in human breast carcinoma MCF-7 cells
2008 |
Central Library of Charles University
publication
The effectiveness of oracin in enhancing the cytotoxicity of doxorubicin through the inhibition of doxorubicin deactivation in breast cancer MCF7 cells
2010 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
The effectiveness of oracin in enhancing the cytotoxicity of doxorubicin through the inhibition of doxorubicin deactivation in breast cancer MCF7 cells
2010 |
Central Library of Charles University
publication
The metabolism of flubendazole in human liver and cancer cell lines
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Anthracyclines and their metabolism in human liver microsomes and the participation of the new microsomal carbonyl reductase
2011 |
Faculty of Pharmacy in Hradec Králové
publication
Human microsomal carbonyl reducing enzymes in the metabolism of xenobiotics: well-known and promising members of the SDR superfamily
2012 |
Faculty of Pharmacy in Hradec Králové
publication
Activity of carbonyl reducing enzymes towards selected pharmacologically and toxicologically relevant substrates
Publication without faculty affiliation
publication
Role of carbonyl reducing enzymes in the phase I biotransformation of the non-steroidal anti-inflammatory drug nabumetone in vitro
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Metabolic profile of mephedrone: Identification of nor-mephedrone conjugates with dicarboxylic acids as a new type of xenobiotic phase II metabolites
2016 |
First Faculty of Medicine