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cell-cycle checkpoints
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Chelidonine and Homochelidonine Induce Cell Death through Cell Cycle Checkpoints and MAP Kinase Pathways
2017 |
Faculty of Medicine in Hradec Králové
publication
Alpha-tomatine activates cell cycle checkpoints in the absence of DNA damage in human leukemic MOLT-4 cells
2013 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Truncated PPM1D Prevents Apoptosis in the Murine Thymus and Promotes Ionizing Radiation-Induced Lymphoma
2020 |
Faculty of Science, Central Library of Charles University
publication
Checkpoint Kinase 1 Is a Key Signal Transducer of DNA Damage in the Early Mammalian Cleavage Embryo
2023 |
First Faculty of Medicine
publication
Clinical Candidates Targeting the ATR-CHK1-WEE1 Axis in Cancer
2021 |
Publication without faculty affiliation
publication
Multiple centrosomes enhance migration and immune cell effector functions of mature dendritic cells
2022 |
First Faculty of Medicine
publication
Targeting the Checkpoint to Kill Cancer Cells
2015 |
Faculty of Science
publication
Nibrin, a novel DNA double-strand break repair protein, is mutated in nijmegen breakage syndrome
1998 |
Second Faculty of Medicine
publication
Genome-wide association study of monoclonal gammopathy of unknown significance (MGUS): comparison with multiple myeloma
2019 |
First Faculty of Medicine, Faculty of Medicine in Pilsen
publication
WIP1 Promotes Homologous Recombination and Modulates Sensitivity to PARP Inhibitors
2019 |
Central Library of Charles University
publication
Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres
2023 |
Central Library of Charles University
publication
Non-apoptotic programmed cell death with paraptotic-like features in bleomycin-treated plant cells is suppressed by inhibition of ATM/ATR pathways or NtE2F overexpression
2012 |
Faculty of Science
publication
Small Molecules Targeting Ataxia Telangiectasia and Rad3-Related (ATR) Kinase: An Emerging way to Enhance Existing Cancer Therapy
2016 |
Publication without faculty affiliation
publication
Telomere maintenance in interplay with DNA repair in pathogenesis and treatment of colorectal cancer
2020 |
First Faculty of Medicine, Faculty of Medicine in Pilsen
publication
Importance of Germline and Somatic Alterations in Human MRE11, RAD50, and NBN Genes Coding for MRN Complex
2023 |
First Faculty of Medicine, Faculty of Science
publication
PPM1D activity promotes the replication stress caused by cyclin E1 overexpression
2023 |
Central Library of Charles University
publication
Extreme variation in apoptosis capacity amongst lymphoid cells of Nijmegen breakage syndrome patients
2008 |
Second Faculty of Medicine
publication
Cancer incidence in Nijmegen breakage syndrome is modulated by the amount of a variant NBS protein
2007 |
Second Faculty of Medicine
publication
Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon
2019 |
First Faculty of Medicine, Faculty of Medicine in Pilsen, Central Library of Charles University
publication
Advanced Microscopy Techniques Used for Comparison of UVA- and gamma-Irradiation-Induced DNA Damage in the Cell Nucleus and Nucleolus
2014 |
First Faculty of Medicine
publication
Attenuated cell cycle and DNA damage response transcriptome signatures and overrepresented cell adhesion processes imply accelerated progression in patients with lower-risk myelodysplastic neoplasms
2024 |
First Faculty of Medicine, Faculty of Science, Faculty of Physical Education and Sport
publication
The Interactions of DNA Repair, Telomere Homeostasis, and p53 Mutational Status in Solid Cancers: Risk, Prognosis, and Prediction
2021 |
First Faculty of Medicine, Faculty of Medicine in Pilsen