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chek2
Publication
Class
Person
Publication
Programmes
publication
Germline CHEK2 Gene Mutations in Hereditary Breast Cancer Predisposition - Mutation Types and their Biological and Clinical Relevance
2019 |
First Faculty of Medicine
publication
Alterations of CHEK2 gene in non-Hodgkin lymphoma patients
Publication without faculty affiliation
publication
Detection of the CHEK2 1100delC mutation in patients with breast cancer
Publication without faculty affiliation
publication
Analysis of CHEK2 FHA domain in Czech patients with sporadic breast cancer revealed distinct rare genetic alterations
2008 |
First Faculty of Medicine
publication
CHEK2 gene alterations in the forkhead-associated domain, 1100delC and del5395 do not modify the risk of sporadic pancreatic cancer.
2010 |
First Faculty of Medicine
publication
Occurrence of CHEK2 1100delC mutation in breast cancer patients and control cohort in the Czech Republic
2005 |
First Faculty of Medicine
publication
Analysis of the c.1100delC mutation of the CHEK2 gene in sporadic colorectal carcinoma and familial adenomatous polyposis patient population
2007 |
First Faculty of Medicine
publication
Functional characterization of CHEK2 variants in a Saccharomyces cerevisiae system
2019 |
First Faculty of Medicine
publication
Alterations of CHEK2 forkhead-associated domain increase the risk of Hodgkin lymphoma
2011 |
First Faculty of Medicine, Second Faculty of Medicine, Third Faculty of Medicine
publication
CHEK2 Germline Variants in Cancer Predisposition: Stalemate Rather than Checkmate
2020 |
First Faculty of Medicine
publication
Identification of deleterious germline CHEK2 mutations and their association with breast and ovarian cancer
2019 |
First Faculty of Medicine
publication
ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk
2023 |
First Faculty of Medicine, Central Library of Charles University
publication
The CHEK2 gene I157T mutation and other alterations in its proximity increase the risk of sporadic colorectal cancer in the Czech population
2009 |
First Faculty of Medicine, Third Faculty of Medicine, Central Library of Charles University
publication
Whole Genome Sequencing Prioritizes CHEK2, EWSR1, and TIAM1 as Possible Predisposition Genes for Familial Non-Medullary Thyroid Cancer
2021 |
Faculty of Medicine in Pilsen
publication
Hereditary breast cancer - new facts
2022 |
First Faculty of Medicine
publication
Association of Germline CHEK2 Gene Variants with Risk and Prognosis of Non-Hodgkin Lymphoma
2015 |
First Faculty of Medicine
publication
The CHEK2 c. 1100delC germline mutation rarely contributes to breast cancer development in the Czech Republic
2005 |
First Faculty of Medicine
publication
Uncommon CHEK2 mis-sense variant and reduced risk of tobacco-related cancers: case-control study
2007 |
First Faculty of Medicine
publication
Uncommon CHEK2 mis-sense variant and reduced risk of tobacco-related cancers: case-control study
2007 |
Faculty of Physical Education and Sport
publication
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer
2014 |
First Faculty of Medicine
publication
The CHEK2 gene I157T mutation and other alterations in its proximity increase the risk of sporadic colorectal cancer in the Czech population
2009 |
Publication without faculty affiliation
publication
Germline BRCA2 K3326X and CHEK2 I157T Mutations Increase Risk for Sporadic Pancreatic Ductal Adenocarcinoma
2019 |
First Faculty of Medicine, Faculty of Medicine in Pilsen
publication
CHEK2*1100delC mutation in the Czech Republic may rarely contribute to breast cancer development
Publication without faculty affiliation
publication
Spectrum of mutations in BRCA1, BRCA2, ATM, and CHEK2 in families at high-risk of breast and ovarian cancer
Publication without faculty affiliation
publication
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer (Reprinted from Nature Genetics vol 46, pg 736, 2014 10.1038/ng.3002)
2014 |
First Faculty of Medicine
publication
Low frequency of CHEK2 1100delC mutation in breast cancer patients and hereditary breast cancer families in the Czech Republic
Publication without faculty affiliation
publication
Higher frequency of non-conservative mutations in fork-head associated (FHA) domain of checkpoint kinase 2 (CHEK2) gene in breast cancer patients
Publication without faculty affiliation
publication
CHEK2p.I157T Mutation Is Associated with Increased Risk of Adult-Type Ovarian Granulosa Cell Tumors
2022 |
Faculty of Medicine in Pilsen
publication
The clinical importance of a genetic analysis of moderate-risk cancer susceptibility genes in breast and other cancer patients from the Czech Republic
2012 |
First Faculty of Medicine
publication
The PALB2 Gene Is a Strong Candidate for Clinical Testing in BRCA1- and BRCA2-Negative Hereditary Breast Cancer
2013 |
First Faculty of Medicine