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cyclosarine
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publication
Relationship between the structure and activity of acetylcholinesterase reactivators. Reactivation of AChE inhibited with cyclosarine
Publication without faculty affiliation
publication
The ability of oxime mixtures to increase the reactivating and therapeutic efficacy of antidotal treatment of cyclosarin poisoning in rats and mice
2012 |
Faculty of Medicine in Hradec Králové
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Synthesis of acetylcholinesterase reactivators and evaluation of their potency to reactivate cyclosarin-inhibited AChE
Publication without faculty affiliation
publication
Twelve different HI-6 salts and their potency to reactivate cyclosarin inhibited AChE in vitro
2007 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
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New group of xylene linker-containing acetylcholinesterase reactivators as antidotes against the nerve agent cyclosarin
2006 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
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New methods in synthesis of acetylcholinesterase reactivators and evaluation of their potency to reactivate cyclosarin-inhibited AChE
2006 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
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Molecular Aspects of the Reactivation Process of Acetylcholinesterase Inhibited by Cyclosarin
2011 |
Publication without faculty affiliation
publication
Reactivation of acetylcholinesterase inhibited with cyclosarine and chlorpyrifos - relationship between structure of reactivators and their reactivation potency
Publication without faculty affiliation
publication
Relationship between the structure of acetylcholine reactivators and their ability to reactivate the enzyme inhibited with cyclosarine and chlorpyriphos
Publication without faculty affiliation
publication
Nerve agents assay using cholinesterase based biosensor
2009 |
Publication without faculty affiliation
publication
Oxime K074-in vitro and in silico reactivation of acetylcholinesterase inhibited by nerve agents and pesticides
2020 |
Publication without faculty affiliation
publication
Targeted synthesis of 1-(4-hydroxyiminomethylpyridinium)-3-pyridiniumpropane dibromide - a new nerve agent reactivator
2007 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
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Tetroxime: reactivation potency - in vitro and in silico study
2017 |
Publication without faculty affiliation
publication
Pyridinium oximes with ortho-positioned chlorine moiety exhibit improved physicochemical properties and efficient reactivation of human Acetylcholinesterase inhibited by several nerve agents
2018 |
Publication without faculty affiliation
publication
Novel acetylcholinesterase reactivator - oxime K048 - reactivation activity in vitro
2010 |
Central Library of Charles University
publication
Oxime K033-reactivation Activity of Cholinesterases Inhibited by Various Nerve Agents and Organophosphorus Pesticides
2018 |
Publication without faculty affiliation
publication
Reactivation kinetics of 31 structurally different bispyridinium oximes with organophosphate-inhibited human butyrylcholinesterase
2015 |
Publication without faculty affiliation
publication
Experimental hydrophilic reactivator: bisoxime with three positive charges
2019 |
Publication without faculty affiliation
publication
Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents
2022 |
Publication without faculty affiliation
publication
Could oxime HI-6 really be considered as 'broad-spectrum' antidote?
2009 |
Central Library of Charles University
publication
Universality of Oxime K203 for Reactivation of Nerve Agent-Inhibited AChE
2015 |
Publication without faculty affiliation
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TRISOXIME - a bulky trisquaternary reactivator of acetylcholinesterase
2016 |
Publication without faculty affiliation
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Butyrylcholinesterase inhibited by nerve agents is efficiently reactivated with chlorinated pyridinium oximes
2019 |
Publication without faculty affiliation
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Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase
2016 |
Publication without faculty affiliation
publication
Could oxime HI-6 really be considered as 'broad-spectrum' antidote?
2009 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
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Reactivation potential of novel more lipophilic pralidoxime analogs
2018 |
Publication without faculty affiliation
publication
OPCW biomedical proficiency test in the laboratory of analytical chemistry at the Department of toxicology and military pharmacy
2020 |
Faculty of Pharmacy in Hradec Králové