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cytochrome P450 (CYP)
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Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method
2009 |
Faculty of Science
publication
DNA adducts from ellipticine after its activation in vitro and in cells transfected with cytochrome P450 (CYP)
2001 |
Faculty of Science
publication
DNA adducts from ellipticine after its activation in vitro and in cells transfected with cytochrome P450 (CYP)
2001 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
Influence of probiotics on rat liver biotransformation enzymes.
2009 |
First Faculty of Medicine
publication
Oxidation of 3-aminobenzanthrone, a human metabolite of carcinogenic environmental pollutant 3-nitrobenzanthrone, by cytochromes P450 – similarity between human and rat enzymes
2009 |
Faculty of Science, First Faculty of Medicine, Faculty of Mathematics and Physics
publication
The binding affinity of carcinogenic N-nitrosodimethylamine and N-nitrosomethylaniline to cytochromes P450 2B4, 2E1 and 3A6 does not dictate the rate of their enzymatic N- demethylation.
2010 |
Faculty of Science
publication
Hepatocellular carcinoma: Gene expression profiling and regulation of xenobiotic-metabolizing cytochromes P450
2020 |
Faculty of Medicine in Pilsen, Faculty of Medicine in Hradec Králové
publication
Alpha-Naphthoflavone acts as activator and reversibile or irreversible inhibitor of rabbit microsomal CYP3A6
2001 |
Faculty of Science
publication
Evaluation of possible inhibition of human liver drug metabolizing cytochromes P450 by two new acetylcholinesterase oxime-type reactivators
2016 |
Publication without faculty affiliation
publication
In vitro and in vivo interaction of flavonoids with CYP microsomal system
2003 |
Faculty of Science
publication
A role of biotransformation enzymes in the Development of renal injury and urothelial cancer caused by aristolochic acid: Urgent questions difficult answers
2009 |
Faculty of Science
publication
Anticancer drug ellipticine forms DNA adducts in vivo; A novel mode of its antineoplatic action
2004 |
Faculty of Science
publication
Oxidation of the carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I) by cytochromes P450 and peroxidases: a comparative study
2009 |
Faculty of Science
publication
Rat cytochromes P450 oxidize 2-nitrophenol, a human metabolite of carcinogenic 2-nitroanisole
2009 |
Faculty of Science
publication
Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma
2011 |
Faculty of Science, Faculty of Physical Education and Sport, First Faculty of Medicine
publication
Post-translational and Post-transcriptional Modifications of Pregnane X Receptor (PXR) in Regulation of the Cytochrome P450 Superfamily
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Sulforaphane Alters beta-Naphthoflavone-Induced Changes in Activity and Expression of Drug-Metabolizing Enzymes in Rat Hepatocytes
2017 |
Faculty of Pharmacy in Hradec Králové
publication
Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver
2011 |
Faculty of Science, Faculty of Physical Education and Sport, First Faculty of Medicine
publication
Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker
2016 |
First Faculty of Medicine
publication
The Anticancer Drug Ellipticine Induces Cytochromes P450 1A1, 1A2 and 3A, Cytochrome b(5) and NADPH:Cytochrome P450 Oxidoreductase in Rat Liver, Kidney and Lung
2013 |
Faculty of Science
publication
Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy
2011 |
Faculty of Science
publication
Photo-cytochrome b(5) - A New Tool to Study the Cytochrome P450 Electron-transport Chain
2013 |
Faculty of Science
publication
Mapping of cytochrome P450 2B4 substrate binding sites by photolabile probe 3-azidiamantane: Identification of putative substrate access regions
2007 |
Faculty of Science
publication
In vivo effects of antiviral acyclic nucleoside phosphonate 9-[2-(phosphonomethoxy)ethyl]adenine (adefovir) on cytochrome P450 system of rat liver microsomes
2006 |
Central Library of Charles University, Faculty of Medicine in Pilsen
publication
Sudan I Is a Potential Carcinogen for Humans: Evidence for Its Metabolic Activation and Detoxication by Human Recombinant Cytochrome P450 1A1 and Liver Microsomes
2002 |
Faculty of Science
publication
The relationship between DNA adduct formation by benzo[a]pyrene and expression of its activation enzyme cytochrome P450 1A1 in rat
2013 |
Faculty of Science
publication
Role of rat cytochromes P450 in the oxidation of 17α-ethinylestradiol
2014 |
Faculty of Science
publication
Structural requirements for inhibitors of cytochromes P4502B: Assessment of the enzyme interaction with diamondoids
2005 |
Faculty of Science, Central Library of Charles University
publication
Serum Levels of Aryl Hydrocarbon Receptor, Cytochromes P450 1A1 and 1B1 in Patients with Exacerbated Psoriasis Vulgaris
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Cytochrome P450 and flavin-containing monooxygenase enzymes are responsible for differential oxidation of the anti-thyroid-cancer drug vandetanib by human and rat hepatic microsomal systems
2020 |
Faculty of Science, Second Faculty of Medicine