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dexrazoxane
Publication
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Person
Publication
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publication
Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death
+1
2009 |
Faculty of Medicine in Hradec Králové
publication
Dexrazoxan - the possibility of protection in patients after chemotherapy and irradiation
1995 |
First Faculty of Medicine
publication
Evaluation of the cardioprotective effect of dexrazoxane during administration of the cardiotoxic antineoplastic drug - daunorubicin
1999 |
Faculty of Medicine in Hradec Králové
publication
Efficacy of Dexrazoxane in Cardiac Protection in Pediatric Patients Treated With Anthracyclines
2023 |
Faculty of Physical Education and Sport
publication
Deferoxamine but not dexrazoxane alleviates liver injury induced by endotoxemia in rats
2014 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Large-Scale Synthesis of Piperazine-2,6-dione and Its Use in the Synthesis of Dexrazoxane Analogues
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Dexrazoxane provided moderate protection in a catecholamine model of severe cardiotoxicity
2012 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death
2009 |
Central Library of Charles University
publication
Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane
2016 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Protective effects of dexrazoxane against acute ischaemia/reperfusion injury of rat hearts
2012 |
Faculty of Medicine in Hradec Králové
publication
Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Development of LC-MS/MS method for the simultaneous analysis of the cardioprotective drug dexrazoxane and its metabolite ADR-925 in isolated cardiomyocytes and cell culture medium
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits
2013 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase II beta Interactions
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case
2011 |
Faculty of Pharmacy in Hradec Králové
publication
Interface-free capillary electrophoresis-mass spectrometry systemwith nanospray ionization-Analysis of dexrazoxane in blood plasma
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Myocardial content of selected elements in experimental anthracycline-induced cardiomyopathy in rabbits
2005 |
First Faculty of Medicine
publication
Effect of Sodium 2,3-dimercaptopropane-1-sulfonate (DMPS) on chronic daunorubicin toxicity in rabbits: comparison with dexrazoxane
2002 |
Publication without faculty affiliation
publication
The effects of pyridoxal isonicotinoyl hydrazone and dexrazoxane on cardiovascular parameters in daunorubicin-induced cardiomyopathy in rabbits
2002 |
Publication without faculty affiliation
publication
Investigation of novel dexrazoxane analogue JR-311 shows significant cardioprotective effects through topoisomerase IIbeta but not its iron chelating metabolite
2017 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Cholinesterases in Dexrazoxane-treated Daunorubicin Cardiomyopathy in Rabbits
1999 |
Faculty of Medicine in Hradec Králové
publication
The effects of pyridoxal isonicotinoyl hydrazone and dexrazoxane on biochemical and haematological parameters in daunorubicin-induced cardiomyopathy in rabbits
2002 |
Publication without faculty affiliation
publication
Synthesis and analysis of novel analogues of dexrazoxane and its open-ring hydrolysis product for protection against anthracycline cardiotoxicity in vitro and in vivo
2015 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Treatment with dexrazoxane (ICRF-187) reduces Myocardial calcium overload in the experimental anthracycline-induced heart failure in rabbits
Publication without faculty affiliation
publication
Pharmacokinetics of the cardioprotective drug dexrazoxane and its active metabolite ADR-925 with focus on cardiomyocytes and the heart
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase II beta Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
ICRF-187 (dexrazoxan) protects from adriamycin-induced nephrotic syndrome in rats
1998 |
Faculty of Physical Education and Sport
publication
ICRP-187 (dexrazoxan) protects from adriamycin-induced nephrotic syndrome in rats.
1998 |
Faculty of Physical Education and Sport
publication
Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death
2009 |
Faculty of Pharmacy in Hradec Králové