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farnesoid X receptor
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publication
Boldine enhances bile production in rats via osmotic and Farnesoid X receptor dependent mechanisms
2015 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
(E)-7-Ethylidene-lithocholic Acid (7-ELCA) Is a Potent Dual Farnesoid X Receptor (FXR) Antagonist and GPBAR1 Agonist Inhibiting FXR-Induced Gene Expression in Hepatocytes and Stimulating Glucagon-like Peptide-1 Secretion From Enteroendocrine Cells
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Science
publication
Gut Microbes Take It to the Next Level? First Insights Into Farnesoid X Receptor Agonists of Microbial Origin
2020 |
First Faculty of Medicine
publication
3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Science
publication
When Two Become One: Conformational Changes in FXR/RXR Heterodimers Bound to Steroidal Antagonists
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Science
publication
Prolonged fibroblast growth factor 19 response in patients with primary sclerosing cholangitis after an oral chenodeoxycholic acid challenge
2017 |
First Faculty of Medicine
publication
The Role of Steroid Hormones in the Development of Intrahepatic Cholestasis of Pregnancy
2015 |
First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Urinary metabolomics in Fxr-null mice reveals activated adaptive metabolic pathways upon bile acid challenge
2010 |
First Faculty of Medicine
publication
Severe bile salt export pump deficiency: 82 different ABCB11 mutations in 109 families
2008 |
Second Faculty of Medicine
publication
Cholic acid therapy in Zellweger spectrum disorders
2016 |
First Faculty of Medicine
publication
Pharmacological importance of orphan nuclear receptors
2014 |
First Faculty of Medicine
publication
New Insights in Genetic Cholestasis: From Molecular Mechanisms to Clinical Implications
2018 |
Third Faculty of Medicine
publication
Serum concentrations of fibroblast growth factor 19 in patients with obesity and type 2 diabetes mellitus: the influence of acute hyperinsulinemia, very-low calorie diet and PPAR-alpha agonist treatment
2011 |
First Faculty of Medicine
publication
Pleiotropic effects of bile acids
2017 |
First Faculty of Medicine
publication
The role of bile acids in metabolic regulation
2016 |
First Faculty of Medicine
publication
Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia
2021 |
First Faculty of Medicine
publication
Bile Acid Malabsorption in Inflammatory Bowel Disease
2015 |
First Faculty of Medicine
publication
Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Ursodeoxycholic Acid but Not Tauroursodeoxycholic Acid Inhibits Proliferation and Differentiation of Human Subcutaneous Adipocytes
2013 |
Third Faculty of Medicine
publication
Induction of fecal cholesterol excretion is not effective for the treatment of hyperbilirubinemia in Gunn rats
2021 |
First Faculty of Medicine
publication
Chyme Reinfusion Restores the Regulatory Bile Salt-FGF19 Axis in Patients With Intestinal Failure
2021 |
First Faculty of Medicine