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mTORC1
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Inhibition of mTORC1 by SU6656, the Selective Src Kinase Inhibitor, Is Not Accompanied by Activation of Akt/PKB Signalling in Melanoma Cells
2013 |
First Faculty of Medicine, Third Faculty of Medicine
publication
Cerebellar demyelination and neurodegeneration associated with mTORC1 hyperactivity may contribute to the developmental onset of autism-like neurobehavioral phenotype in a rat model
2022 |
Third Faculty of Medicine, Central Library of Charles University
publication
Involvement of c-Src activity in the mTOR-dependent oncogenicity of melanoma cells
Publication without faculty affiliation
publication
Regulation of mTORC1 signaling by Src kinase activity is Akt1-independent in RSV-transformed cells
2008 |
First Faculty of Medicine
publication
Developmental effects of constitutive mTORC1 hyperactivity and environmental enrichment on structural synaptic plasticity and behaviour in a rat model of autism spectrum disorder
2023 |
First Faculty of Medicine, Faculty of Science, Central Library of Charles University
publication
Activity of c-Src as a novel target for the inhibition of mTOR signaling in human diseases
Publication without faculty affiliation
publication
The landscape of epilepsy-related GATOR1 variants
2019 |
Second Faculty of Medicine
publication
A Role of PI3K/Akt Signaling in Oocyte Maturation and Early Embryo Development
2023 |
Faculty of Science
publication
Integrated actions of mTOR complexes 1 and 2 for growth and development of Dictyostelium
2019 |
Faculty of Science
publication
MicroRNA-34a activation in tuberous sclerosis complex during early brain development may lead to impaired corticogenesis
2021 |
Second Faculty of Medicine
publication
The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas
2020 |
Second Faculty of Medicine
publication
Involvement of mTOR Pathways in Recovery from Spinal Cord Injury by Modulation of Autophagy and Immune Response
2021 |
Second Faculty of Medicine
publication
Contemporary mTOR inhibitor scaffolds to diseases breakdown: A patent review (2015-2021)
2022 |
Publication without faculty affiliation
publication
Revisiting Brain Tuberous Sclerosis Complex in Rat and Human: Shared Molecular and Cellular Pathology Leads to Distinct Neurophysiological and Behavioral Phenotypes
2021 |
Third Faculty of Medicine
publication
The Role of Green Tea Catechin Epigallocatechin Gallate (EGCG) and Mammalian Target of Rapamycin (mTOR) Inhibitor PP242 (Torkinib) in the Treatment of Spinal Cord Injury
2023 |
Second Faculty of Medicine
publication
Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics
2022 |
Faculty of Medicine in Hradec Králové
publication
TSC/mTOR pathway mutation associated eosinophilic/oncocytic renal neoplasmsm: a heterogeneous group of tumors with distinct morhpology, immunohistochemical profile, and similar genetic background
2022 |
Faculty of Medicine in Pilsen
publication
mTOR as an eligible molecular target for possible pharmacological treatment of nonalcoholic steatohepatitis
2022 |
First Faculty of Medicine
publication
Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8(+) T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness
2019 |
Second Faculty of Medicine
publication
Acute Conditioning of Antigen-Expanded CD8(+) T Cells via the GSK3β-mTORC Axis Differentially Dictates Their Immediate and Distal Responses after Antigen Rechallenge
2020 |
Second Faculty of Medicine
publication
Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment
2017 |
Second Faculty of Medicine
publication
Novel Histopathological Patterns in Cortical Tubers of Epilepsy Surgery Patients with Tuberous Sclerosis Complex
2016 |
Second Faculty of Medicine