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oxime reactivators
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The interaction of standard oxime reactivators with hemicholinium-3 sensitive choline carriers
2012 |
Publication without faculty affiliation
publication
The summary on non-reactivation cholinergic properties of oxime reactivators: the interaction with muscarinic and nicotinic receptors
2013 |
Publication without faculty affiliation
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Effect of P-glycoprotein on the availability of oxime reactivators in the brain
2020 |
Publication without faculty affiliation
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Strategies for enhanced bioavailability of oxime reactivators in the central nervous system
2023 |
Publication without faculty affiliation
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Current approaches to enhancing oxime reactivator delivery into the brain
2019 |
Publication without faculty affiliation
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Pharmacological and toxicological in vitro and in vivo effect of higher doses of oxime reactivators
2019 |
Publication without faculty affiliation
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Novel bisquaternary oximes - reactivation of acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon
2009 |
Central Library of Charles University
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Novel bisquaternary oximes - reactivation of acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon
2009 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
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In Vitro Evaluation of Oxidative Stress Induced by Oxime Reactivators of Acetylcholinesterase in HepG2 Cells
2023 |
Faculty of Pharmacy in Hradec Králové
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Reactivation of Human Acetylcholinesterase and Butyrylcholinesterase Inhibited by Leptophos-Oxon with Different Oxime Reactivators in Vitro
2010 |
Publication without faculty affiliation
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In vitro screening of oxime reactivators on the model of paraoxon-inhibited acetylcholinesterase - SAR study
2010 |
Central Library of Charles University
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Determination of K869, a Novel Oxime Reactivator of Acetylcholinesterase, in Rat Body Fluids and Tissues by Liquid-Chromatography Methods: Pharmacokinetic Study
2021 |
Faculty of Pharmacy in Hradec Králové
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New acetylcholinesterase reactivators bearing a xylene linker - synthesis and in vitro testing
Publication without faculty affiliation
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Synthesis of new acetylcholinesterase reactivators with reduced toxicity
Publication without faculty affiliation
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Reactivator K203 development
Publication without faculty affiliation
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Reactivation kinetics of 31 structurally different bispyridinium oximes with organophosphate-inhibited human butyrylcholinesterase
2015 |
Publication without faculty affiliation
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In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?
2018 |
Faculty of Pharmacy in Hradec Králové
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Acid dissociation constants and molecular descriptors of some xylene linked bispyridinium oximes
2015 |
First Faculty of Medicine
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Bisquaternary oximes as reactivators of tabun-inhibited human brain cholinesterases: an in vitro study
2007 |
Publication without faculty affiliation
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Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase
2016 |
Publication without faculty affiliation
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Comparison of plasma and brain exposure levels of bis-pyridinium oximes KR-22839 and KR-26256 with asoxime and obidoxime in mice
2019 |
Publication without faculty affiliation
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Novel acetylcholinesterase reactivator - oxime K048 - reactivation activity in vitro
2010 |
Central Library of Charles University
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Development and Structural Modifications of Cholinesterase Reactivators against Chemical Warfare Agents in Last Decade: A Review
2015 |
First Faculty of Medicine
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Reactivation of human brain homogenate cholinesterases inhibited by tabun using newly developed oximes K117 and K127
+1
2009 |
Central Library of Charles University
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SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides
2016 |
Publication without faculty affiliation
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Butyrylcholinesterase inhibited by nerve agents is efficiently reactivated with chlorinated pyridinium oximes
2019 |
Publication without faculty affiliation
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Tacroximes: novel unique compounds for the recovery of organophosphorus-inhibited acetylcholinesterase
2019 |
Publication without faculty affiliation
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Development of versatile and potent monoquaternary reactivators of acetylcholinesterase
2021 |
Publication without faculty affiliation
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Countermeasures in organophosphorus intoxication: pitfalls and prospects
2022 |
Publication without faculty affiliation