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pi3k
Publication
Class
Person
Publication
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publication
Alpelisib - the first PI3K inhibitor in the treatment of hormone-positive, HER2-negative breast cancer
2021 |
First Faculty of Medicine
publication
Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)
2023 |
Publication without faculty affiliation
publication
Genetic defects in PI3K delta affect B-cell differentiation and maturation leading to hypogammaglobulineamia and recurrent infections
2017 |
Second Faculty of Medicine
publication
Phosphatidylinositol 3-Kinase (PI3K) and Phosphatidylinositol 3-Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring
2015 |
Publication without faculty affiliation
publication
Effective "activated PI3K delta syndrome"-targeted therapy with the PI3Kd inhibitor leniolisib
2017 |
Second Faculty of Medicine
publication
Preclinical Evaluation of a Novel SHIP1 Phosphatase Activator for Inhibition of PI3K Signaling in Malignant B Cells
2020 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Sensitivity to PI3K and AKT inhibitors is mediated by divergent molecular mechanisms in subtypes of DLBCL
2017 |
First Faculty of Medicine
publication
Mechanical allodynia and enhanced responses to capsaicin are mediated by PI3K in a paclitaxel model of peripheral neuropathy
2019 |
Faculty of Science
publication
Glycosylation regulates NK cell-mediated effector function through PI3K pathway
2010 |
Central Library of Charles University
publication
Treatment of HER2-positive breast cancer in 2020
2020 |
First Faculty of Medicine
publication
The MEK-ERK-MST1 Axis Potentiates the Activation of the Extrinsic Apoptotic Pathway during GDC-0941 Treatment in Jurkat T Cells
2019 |
Central Library of Charles University, Faculty of Science
publication
Alpelisib
2021 |
Third Faculty of Medicine
publication
Dual PI3Kδ/γ Inhibitor Duvelisib Prevents Development of Neuropathic Pain in Model of Paclitaxel-Induced Peripheral Neuropathy
2022 |
Central Library of Charles University
publication
Contemporary mTOR inhibitor scaffolds to diseases breakdown: A patent review (2015-2021)
2022 |
Publication without faculty affiliation
publication
Progress report of project realization "Morpholine inhibitors of DNA-dependent protein kinase as a potential radio-and chemosensitizing agent of tumor cells "
Publication without faculty affiliation
publication
DNA-proteinkinase inhibition; oncology treatment; chemosensitization
Publication without faculty affiliation
publication
Molecular Targets for Cancer Therapy in the PI3K/AKT/mTOR Pathway
2014 |
Faculty of Medicine in Pilsen
publication
Activated Phosphoinositide 3-Kinase δ Syndrome: Update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity
2023 |
Second Faculty of Medicine
publication
Parsaclisib, a PI3Kδ inhibitor, in relapsed and refractory follicular lymphoma (CITADEL-203): a phase 2 study
2023 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Natural Course of Activated Phosphoinositide 3-Kinase Delta Syndrome in Childhood and Adolescence
2021 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Parsaclisib, a PI3Kδ inhibitor, in relapsed and refractory mantle cell lymphoma (CITADEL-205): a phase 2 study
2023 |
First Faculty of Medicine
publication
Analysis of 5-Azacytidine Resistance Models Reveals a Set of Targetable Pathways
2022 |
First Faculty of Medicine
publication
Targeting phosphatidylinositol 3 kinase-beta and -delta for Bruton tyrosine kinase resistance in diffuse large B-cell lymphoma
2020 |
First Faculty of Medicine
publication
The Possible Role of mRNA Expression Changes of GH/IGF-1/Insulin Axis Components in Subcutaneous Adipose Tissue in Metabolic Disturbances of Patients With Acromegaly
2016 |
First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Small Molecules in the Treatment of Chronic Lymphocytic Leukemia in 2015 and in the Near Future
2015 |
First Faculty of Medicine
publication
Molecular mechanisms of primary and secondary resistance, molecular-genetic features and characteristics of KIT/PDGFRA non-mutated GISTs
2017 |
Second Faculty of Medicine
publication
Combination Treatment Targeting mTOR and MAPK Pathways Has Synergistic Activity in Multiple Myeloma
2023 |
First Faculty of Medicine
publication
Structural basis for the 14-3-3 protein-dependent inhibition of apoptosis signal-regulating kinase 1
Publication without faculty affiliation
publication
Alpelisib v léčbě pacientky s karcinomem prsu - kazuistika
2022 |
First Faculty of Medicine
publication
Is there a benefit of HER2-positive breast cancer subtype determination in clinical practice?
2019 |
First Faculty of Medicine, Third Faculty of Medicine