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poly(ADP‐ ribose) polymerase
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The Importance of Poly(ADP-Ribose) Polymerase as a Sensor of Unligated Okazaki Fragments during DNA Replication
2018 |
Central Library of Charles University
publication
Bcl-2 prevents nitric oxide-mediated apoptosis and poly (ADP-ribose) polymerase clevage.
1998 |
Faculty of Physical Education and Sport
publication
Pharmacokinetics and safety of rucaparib in patients with advanced solid tumors and hepatic impairment
2021 |
First Faculty of Medicine
publication
Pharmacokinetics and safety of olaparib in patients with advanced solid tumours and mild or moderate hepatic impairment
2020 |
Publication without faculty affiliation
publication
Olaparib as a maintenance therapy in newly diagnosed patients with ovarian cancer - SOLO1 study results
2022 |
Third Faculty of Medicine
publication
Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures
2021 |
Central Library of Charles University
publication
Rucaparib versus standard-of-care chemotherapy in patients with relapsed ovarian cancer and a deleterious BRCA1 or BRCA2 mutation (ARIEL4): an international, open-label, randomised, phase 3 trial
2022 |
First Faculty of Medicine
publication
Nové možnosti léčby pacientek s mutacemi genů BRCA1/2 a karcinomem ovarií
2017 |
First Faculty of Medicine
publication
Benefit of olaparib in the treatment of ovarian cancer – clinical practice
2023 |
Third Faculty of Medicine
publication
The use of niraparib in the treatment of ovarian cancer
2023 |
First Faculty of Medicine
publication
Platinum-sensitive recurrent ovarian cancer and olaparib maintenance treatment - case report
2019 |
First Faculty of Medicine
publication
Niraparib expands the availability of maintenance therapy in patients with advanced high-grade ovarian cancer
2022 |
Faculty of Medicine in Pilsen
publication
PARP inhibitors in treating metastatic castration-resistant prostate cancer
2023 |
First Faculty of Medicine
publication
Treatment strategy of triple negative breast cancer in young women - do we treat them differently?
2023 |
First Faculty of Medicine
publication
Randomized phase III trial on niraparib-TSR-042 (dostarlimab) versus physician's choice chemotherapy in recurrent ovarian, fallopian tube, or primary peritoneal cancer patients not candidate for platinum retreatment: NItCHE trial (MITO 33)
2021 |
Publication without faculty affiliation
publication
Novel modified leucine and phenylalanine dipeptides modulate viability and attachment of cancer cells
2020 |
Faculty of Science
publication
WIP1 Promotes Homologous Recombination and Modulates Sensitivity to PARP Inhibitors
2019 |
Central Library of Charles University
publication
Olaparib Synergizes the Anticancer Activity of Daunorubicin via Interaction with AKR1C3
2020 |
Faculty of Pharmacy in Hradec Králové
publication
CRISPR/Cas9-Mediated Correction of the FANCD1 Gene in Primary Patient Cells
2017 |
Second Faculty of Medicine
publication
The SC-35 Splicing Factor Interacts with RNA Pol II and A-Type Lamin Depletion Weakens This Interaction
2021 |
First Faculty of Medicine
publication
Genetic testing in ovarian cancer
2022 |
First Faculty of Medicine
publication
Sensitivity of cells to apoptosis induced by iron deprivation can be reversibly changed by iron availability
2006 |
Central Library of Charles University, Third Faculty of Medicine
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Testing of mutations in BRCA1 and BECA2 genes in tumor tissues - possibilities and limitations
2016 |
Faculty of Medicine in Hradec Králové
publication
BRCA1 and BRCA2 - pathologist's starting kit
2016 |
Second Faculty of Medicine
publication
European experts consensus: BRCA/homologous recombination deficiency testing in first-line ovarian cancer
Publication without faculty affiliation
publication
Niraparib and Abiraterone Acetate for Metastatic Castration-Resistant Prostate Cancer
Publication without faculty affiliation