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pregnane-x-receptor
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Rifampicin-Activated Human Pregnane X Receptor and CYP3A4 Induction Enhance Acetaminophen-Induced Toxicity
2009 |
First Faculty of Medicine
publication
The pregnane X receptor: from bench to bedside
2008 |
First Faculty of Medicine
publication
Dietary phytochemicals as modulators of human pregnane X receptor
2023 |
Faculty of Pharmacy in Hradec Králové
publication
Pregnane X Receptor and Cancer: Context-Specificity is Key
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Resveratrol as an Inhibitor of Pregnane X Receptor (PXR): Another Lesson in PXR Antagonism
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Pregnane xenobiotic receptors and their effect on drug elimination from the organism
2013 |
First Faculty of Medicine
publication
The role of residues T248, Y249 and T422 in the function of human pregnane X receptor
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Mathematical Models in the Description of Pregnane X Receptor (PXR)-Regulated Cytochrome P450 Enzyme Induction
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Science
publication
Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression
2008 |
Central Library of Charles University
publication
Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Allosteric Antagonism of the Pregnane X Receptor (PXR): Current-State-of-the-Art and Prediction of Novel Allosteric Sites
2022 |
Faculty of Pharmacy in Hradec Králové
publication
The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver
2019 |
Faculty of Pharmacy in Hradec Králové, Third Faculty of Medicine
publication
Post-translational and Post-transcriptional Modifications of Pregnane X Receptor (PXR) in Regulation of the Cytochrome P450 Superfamily
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Marine Ligands of the Pregnane X Receptor (PXR): An Overview
2019 |
Faculty of Pharmacy in Hradec Králové
publication
A Double Transgenic Mouse Model Expressing Human Pregnane X Receptor and Cytochrome P450 3A4
2008 |
First Faculty of Medicine
publication
U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Role of pregnane X receptor in control of all-trans retinoic acid (ATRA) metabolism and its potential contribution to ATRA resistance
2008 |
First Faculty of Medicine
publication
The pregnane X receptor gene-humanized mouse: A model for investigating drug-drug interactions mediated by cytochromes P450 3A
2007 |
First Faculty of Medicine
publication
The pregnane X receptor gene-humanized mouse: A model for investigating drug-drug interactions mediated by cytochromes P450 3A
2007 |
Faculty of Physical Education and Sport
publication
Pregnane X receptor polymorphisms in patients with inflammatory bowel diseases
Publication without faculty affiliation
publication
Rifaximin is a gut-specific human pregnane X receptor activator
2007 |
First Faculty of Medicine
publication
Rifaximin is a gut-specific human pregnane X receptor activator
2007 |
Faculty of Physical Education and Sport
publication
Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways
2007 |
Publication without faculty affiliation
publication
Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways
2007 |
Faculty of Pharmacy in Hradec Králové
publication
Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene
2011 |
Faculty of Pharmacy in Hradec Králové
publication
Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions
2016 |
Faculty of Pharmacy in Hradec Králové
publication
The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression
2008 |
Faculty of Pharmacy in Hradec Králové, Central Library of Charles University