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Search for publications relevant for "target-directed ligands"
target-directed ligands
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publication
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease
2019 |
Central Library of Charles University, Faculty of Medicine in Hradec Králové
publication
Turning Donepezil into a Multi-Target-Directed Ligand through a Merging Strategy
2021 |
Publication without faculty affiliation
publication
Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer's Disease
2021 |
Publication without faculty affiliation
publication
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease
2017 |
Publication without faculty affiliation
publication
Riluzole-Rasagiline Hybrids: Toward the Development of Multi-Target-Directed Ligands for Amyotrophic Lateral Sclerosis
2022 |
Publication without faculty affiliation
publication
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease
Publication without faculty affiliation
publication
Derivatives of the beta-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer's Disease
2019 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Profiling donepezil template into multipotent hybrids with antioxidant properties
2018 |
Publication without faculty affiliation
publication
Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity
2015 |
Publication without faculty affiliation
publication
2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease
2021 |
Publication without faculty affiliation
publication
Conjugates on the basis of tacrine and tryptophan, a method of their preparation and their use
Publication without faculty affiliation
publication
Donepezil derivatives targeting amyloid-beta cascade in Alzheimer's disease
2019 |
Publication without faculty affiliation
publication
Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives
2019 |
Publication without faculty affiliation
publication
Huprine Y-Tryptophan heterodimers with potential implication to Alzheimer's disease treatment
2021 |
Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine
publication
The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease
2018 |
Faculty of Pharmacy in Hradec Králové
publication
The pharmacology of tacrine at N-methyl-D-aspartate receptors
2017 |
Publication without faculty affiliation
publication
New dual small molecules for Alzheimer's disease therapy combining histamine H-3 receptor (H3R) antagonism and calcium channels blockade with additional Cholinesterase inhibition
2019 |
Publication without faculty affiliation
publication
Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-D-Aspartate Receptor Antagonists
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Science
publication
Structure-Guided Design of N-Methylpropargylamino- Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Science
publication
Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile
2020 |
Publication without faculty affiliation
publication
Huprines - an insight into the synthesis and biological properties
2020 |
Publication without faculty affiliation
publication
Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer's disease treatment
2017 |
Publication without faculty affiliation
publication
7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment
2015 |
Publication without faculty affiliation
publication
Tacrine and its derivatives in the therapy of Alzheimer's disease
2012 |
Publication without faculty affiliation
publication
7-Methoxytacrine-Adamantylamine Heterodimers as Cholinesterase Inhibitors in Alzheimer's Disease Treatment - Synthesis, Biological Evaluation and Molecular Modeling Studies
2013 |
Publication without faculty affiliation
publication
Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment
2017 |
Publication without faculty affiliation
publication
Novel propargylamine-based inhibitors of cholinesterases and monoamine oxidases: Synthesis, biological evaluation and docking study
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Multitarget tacrine hybrids with neuroprotective properties to confront Alzheimer's disease
2017 |
Publication without faculty affiliation
publication
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase
2019 |
Publication without faculty affiliation
publication
Combination of Memantine and 6-Chlorotacrine as Novel Multi-Target Compound against Alzheimer's Disease
2019 |
Publication without faculty affiliation