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thiopurines
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Azathioprine in the therapy of paediatric inflammatory bowel disease - part I: treatment indications, dosing and thiopurine-related adverse events
2021 |
Second Faculty of Medicine
publication
Azathioprine in the therapy of paediatric inflammatory bowel disease - part II: pharmacodynamics, pharmacokinetics, and the possibilities of measuring its metabolites in clinical practice
2021 |
Second Faculty of Medicine
publication
Complication of immunosupresive therapy thiopurine in patients with inflammatory bowel disease
Publication without faculty affiliation
publication
Identification of predictive factors of AZA/6-MP treatment outcome in peadiatric Crohn's disease
2017 |
Second Faculty of Medicine
publication
Augmenting Clinical Interpretability of Thiopurine Methyltransferase Laboratory Evaluation
2014 |
Second Faculty of Medicine
publication
Is It Useful to Monitor Thiopurine Metabolites in Pediatric Patients with Crohn's Disease on Combination Therapy? A Multicenter Prospective Observational Study
2021 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Thiopurine-induced toxicity is associated with dysfunction variant of the human molybdenum cofactor sulfurase gene (xanthinuria type II)
2018 |
First Faculty of Medicine
publication
Thiopurine intolerance-causing mutations in NUDT15 induce temperature-dependent destabilization of the catalytic site
2019 |
Faculty of Science
publication
Prediction of thiopurine failure in pediatric Crohn's disease: pediatric IBD Porto group of ESPGHAN
2023 |
Second Faculty of Medicine, Faculty of Medicine in Pilsen, Faculty of Mathematics and Physics, Faculty of Medicine in Hradec Králové
publication
Azathioprine myelosuppression in multiple sclerosis: characterizing thiopurine methyltransferase polymorphisms
2006 |
First Faculty of Medicine
publication
Azathioprine myelosuppression in multiple sclerosis: characterizing thiopurine methyltransferase polymorphisms
2006 |
Faculty of Physical Education and Sport
publication
Azathioprine myelosupression in multiple sclerosis: characterizing thiopurine methyltransferase polymorphisms
2006 |
First Faculty of Medicine
publication
Azathioprine myelosupression in multiple sclerosis: characterizing thiopurine methyltransferase polymorphisms
2006 |
Faculty of Physical Education and Sport
publication
Effects of the activity of thiopurin metyltransferase on the results of long-term immunosupressive therapy with azathioprin (6-mercaptopurine) in patients with inflammatory bowel diseases
2002 |
Faculty of Physical Education and Sport
publication
Long-term therapy of idiopathic inflammatory bowel disease
2012 |
First Faculty of Medicine
publication
Thiopurine methyltransferase (TPMT) activity in patients with IBD: the influence on the results of the long term azathioprine (AZA) therapy
Publication without faculty affiliation
publication
Monitoring of thiopurine methyltransferase activity in postsurgical patients with Crohn's disease during 1 year of treatment with azathioprine or mesalazine
2007 |
First Faculty of Medicine
publication
Monitoring of thiopurine methyltransferase activity in postsurgical patients with Crohn's disease during 1 year of treatment with azathioprine or mesalazine
2007 |
Faculty of Physical Education and Sport
publication
Prediction of Thiopurine Metabolite Levels Based on Haematological and Biochemical Parameters
2019 |
Second Faculty of Medicine
publication
Polymorphisms of the TPMT gene in the Czech healthy population and patients with inflammatory bowel disease
2008 |
First Faculty of Medicine
publication
Thiopurine methyltransferase activity, 6-methylmercaptopurin and 6-thioguanin levels in patients with IBD: the influence on adverse events of azathioprine therapy
Publication without faculty affiliation
publication
Thiopurine methyltransferase activity, 6methylmercaptopurine and 6-thioguanine levels in patients with IBD: the influence on adverse events of azathioprine therapy
Publication without faculty affiliation
publication
Effects of the activity of thiopurin metyltransferase on the results of long-term immunosupressive therapy with azathioprin (6-mercaptopurine) in patients with inflammatory bowel diseases
2002 |
First Faculty of Medicine
publication
Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis
2011 |
First Faculty of Medicine
publication
Malignancy and mortality in paediatric-onset inflammatory bowel disease: a 3-year prospective, multinational study from the paediatric IBD Porto group of ESPGHAN
2018 |
Second Faculty of Medicine
publication
When and how to proceed with postoperative recurrence of Crohn's disease
2016 |
First Faculty of Medicine
publication
Editorial: Idiopathic intestinal inflammation in childhood
2017 |
Second Faculty of Medicine, Faculty of Medicine in Pilsen
publication
Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care-An Evidence-based Guideline From European Crohn's and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition
2018 |
Second Faculty of Medicine
publication
COST action B25 - Physiologically based pharmaco-toxico-kinetics and dynamics: expert meeting on "From models to individual patients" (from in silico to bedside)
Publication without faculty affiliation
publication
Sclerosing cholangitis in children with inflammatory bowel disease
2023 |
Second Faculty of Medicine