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trimedoxime
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A comparison of reactivation and therapeutic efficacy of the oxime K203 and its fluorinated analog (KR-22836) with currently available oximes (obidoxime, trimedoxime, HI-6) against tabun in rats and mice
2010 |
Faculty of Medicine in Hradec Králové
publication
The effect of trimedoxime on acetylcholinesterase and on the cholinergic system of the rat bladder
2010 |
Central Library of Charles University
publication
Capability testing of well-known oximes (pralidoxime, trimedoxime, HI-6, methoxime, obidoxime) to reactivate in vitro chlorpyrifos-inhibited acetylcholinesterase
Publication without faculty affiliation
publication
Pharmacokinetic study of two acetylcholinesterase reactivators, trimedoxime and newly synthesized oxime K027, in rat plasma
2013 |
Faculty of Medicine in Hradec Králové
publication
Understanding the interaction modes and reactivity of trimedoxime towardMmAChE inhibited by nerve agents: Theoretical and experimental aspects
2020 |
Publication without faculty affiliation
publication
The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of soman poisoning in rats and mice
+1
2009 |
Faculty of Medicine in Hradec Králové
publication
In vitro effects of acetylcholinesterase reactivators on monoamine oxidase activity
2011 |
First Faculty of Medicine
publication
The Evaluation of the Reactivating and Neuroprotective Efficacy of Two Newly Prepared Bispyridinium Oximes (K305, K307) in Tabun-Poisoned Rats-A Comparison with Trimedoxime and the Oxime K203
2017 |
Publication without faculty affiliation
publication
Partition of bispyridinium oximes (trimedoxime and K074) administered in therapeutic doses into different parts of the rat brain
2011 |
Publication without faculty affiliation
publication
Relationship between the structure and activity of acetylcholinesterase reactivators. Reactivation of AChE inhibited with cyclosarine
Publication without faculty affiliation
publication
Relationship between the structure and activity of acetylcholinesterase reactivators. Reactivation of AChE inhibited with pesticides
Publication without faculty affiliation
publication
In vitro effects of acetylcholinesterase reactivators on monoamine oxidase activity
2011 |
Faculty of Physical Education and Sport, First Faculty of Medicine
publication
Reactivation of human brain homogenate cholinesterases inhibited by tabun using newly developed oximes K117 and K127
+1
2009 |
Central Library of Charles University
publication
Acetylcholinesterase reactivators (HI-6, obidoxime, trimedoxime, K027, K075, K127, K203, K282): structural evaluation of human serum albumin binding and absorption Kinetics
2013 |
Publication without faculty affiliation
publication
The benefit of combinations of oximes for the ability of antidotal treatment to counteract sarin-induced brain damage in rats
2018 |
Publication without faculty affiliation
publication
Synthesis of series of new acetlcholineesterase reactivators bearing but-2-ine linker and their in vitro evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase
Publication without faculty affiliation
publication
Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro
2008 |
Central Library of Charles University
publication
The benefit of combinations of oximes for the reactivating and therapeutic efficacy of antidotal treatment of sarin poisoning in rats and mice
2011 |
Faculty of Medicine in Hradec Králové
publication
A comparison of the reactivating and therapeutic efficacy of chosen combinations of oximes with individual oximes against VX in rats and mice
2011 |
Faculty of Medicine in Hradec Králové
publication
The ability of oxime mixtures to increase the reactivating and therapeutic efficacy of antidotal treatment of cyclosarin poisoning in rats and mice
2012 |
Faculty of Medicine in Hradec Králové
publication
A comparison of the reactivating and therapeutic efficacy of newly developed bispyridinium oximes (K250, K251) with commonly used oximes against tabun in rats and mice
2009 |
Central Library of Charles University
publication
From pyridinium-based to centrally active acetylcholinesterase reactivators
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Synthesis of acetylcholinesterase reactivators and evaluation of their potency to reactivate cyclosarin-inhibited AChE
Publication without faculty affiliation
publication
Targeted synthesis of 1-(4-hydroxyiminomethylpyridinium)-3-pyridiniumpropane dibromide - a new nerve agent reactivator
2007 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
publication
The interaction of standard oxime reactivators with hemicholinium-3 sensitive choline carriers
2012 |
Publication without faculty affiliation
publication
A comparison of the efficiacy of new asymmetric bispyridinium oximes (K027, K048) with currently available oximes against tabun by in vivo methods
2006 |
Faculty of Pharmacy in Hradec Králové
publication
Russian VX: Inhibition and reactivation of acetylcholinesterase compared with VX agent
2006 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
publication
Reactivation of human brain homogenate cholinesterases inhibited by tabun using newly developed oximes K117 and K127
2009 |
Central Library of Charles University, Faculty of Pharmacy in Hradec Králové