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- CYP1A1/2 and prostaglandin H synthase catalyze reductive activation of inflammatory drug aristolochic acid and that results in DNA adduct formation2000 | Přírodovědecká fakulta
- The anticancer drug ellipticine acts as an inducer of cytochromes P450 1A1/2 and potentiates its own pharmacological efficiency2003 | Přírodovědecká fakulta
- Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy2011 | Přírodovědecká fakulta
- Protinádorové léčivo elipticin tvoří adukty s DNA in vivo; nový mechanismus jeho antineoplastického účinku2004 | Přírodovědecká fakulta
- Identification of microsomal enzymes activating carcinogenic aristolochic acid in human2003 | Přírodovědecká fakulta
- Identification of microsomal enzymes activating carcinogenic aristolochic acid in human2003 | 1. lékařská fakulta, Matematicko-fyzikální fakulta
- ANTICANCER DRUG ELLIPTICINE ACTS AS AN INDUCER OF CYTOCHROMES P450 1A1/2 AND POTENTIATES ITS OWN PHARMACOLOGICAL EFFICIENCY2003 | Přírodovědecká fakulta
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- The anticancer drug ellipticine acts as an inducer of cytochromes P450 1A1/2 and potentiates its own pharmacological efficiency2003 | 1. lékařská fakulta, Matematicko-fyzikální fakulta
- Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes2009 | Ústřední knihovna
- Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes2009 | Farmaceutická fakulta v Hradci Králové
- Induction of xenobiotic-metabolizing enzymes in hepatocytes by beta-naphthoflavone: Time-dependent changes in activities, protein and mRNA levels2018 | Farmaceutická fakulta v Hradci Králové
- Role of dihydromyricetin in cytochrome P450-mediated metabolism and carcinogen activation2015 | Přírodovědecká fakulta, Farmaceutická fakulta v Hradci Králové
- Impact of beta-naphthoflavone on genotoxicity of food-derived carcinogens2011 | Přírodovědecká fakulta
- Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model2011 | Přírodovědecká fakulta, 1. lékařská fakulta, Fakulta tělesné výchovy a sportu
- Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model2011 | 2. lékařská fakulta
- Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo2016 | Přírodovědecká fakulta
- Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes2021 | Přírodovědecká fakulta
- The effect of benzo[a]pyrene on metabolic activation of anticancer drug ellipticine in mice2013 | Přírodovědecká fakulta
- The Anticancer Drug Ellipticine Induces Cytochromes P450 1A1, 1A2 and 3A, Cytochrome b(5) and NADPH:Cytochrome P450 Oxidoreductase in Rat Liver, Kidney and Lung2013 | Přírodovědecká fakulta
- Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats2011 | Přírodovědecká fakulta
- The relationship between DNA adduct formation by benzo[a]pyrene and expression of its activation enzyme cytochrome P450 1A1 in rat2013 | Přírodovědecká fakulta
- Impact of smoking on metabolic changes and effectiveness of drugs used for lung cancer2020 | 1. lékařská fakulta
- Mechanisms of Enzyme-Catalyzed Reduction of Two Carcinogenic Nitro-Aromatics, 3-Nitrobenzanthrone and Aristolochic Acid I: Experimental and Theoretical Approaches2014 | Přírodovědecká fakulta
- Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B12012 | Přírodovědecká fakulta
- The Anticancer Drug Ellipticine Activated with Cytochrome P450 Mediates DNA Damage Determining Its Pharmacological Efficiencies: Studies with Rats, Hepatic Cytochrome P450 Reductase Null (HRN (TM)) Mice and Pure Enzymes2015 | Přírodovědecká fakulta
- Enzymes Metabolizing Aristolochic Acid and their Contribution to the Development of Aristolochic Acid Nephropathy and Urothelial Cancer2013 | Přírodovědecká fakulta
- Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver2011 | 2. lékařská fakulta