- Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids2022 | Farmaceutická fakulta v Hradci Králové
- Valproate activates ERK signaling pathway in primary human hepatocytes2014 | Farmaceutická fakulta v Hradci Králové
- Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells2010 | Ústřední knihovna
- Activation of human aryl hydrocarbon receptor in primary human hepatocytes and HepG2 cells by c-Jun-N-terminal kinase inhibitor SP600125Publikace bez příslušnosti k fakultě
- Rifampicin does not significantly affect the expression of small heterodimer partner in primary human hepatocytes2012 | Farmaceutická fakulta v Hradci Králové
- Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4alpha upregulation in primary human hepatocytes2013 | Farmaceutická fakulta v Hradci Králové
- JNK inhibitor SP600125 je parciální agonista AhR receptoru a reguluje CYP1A1 a CYP1A2 v kulturách lidských hepatocytů2008 | Ústřední knihovna
- JNK inhibitor SP600125 is a partial agonist of human aryl hydrocarbon receptor and induces CYP1A1 and CYP1A2 genes in primary human hepatocytes2008 | Farmaceutická fakulta v Hradci Králové
- Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T2013 | Farmaceutická fakulta v Hradci Králové
- Toll-like receptor dual-acting agonists are potent inducers of PBMC-produced cytokines that inhibit hepatitis B virus production in primary human hepatocytes2020 | Přírodovědecká fakulta, 2. lékařská fakulta
- 3D microperfusion of mesoscale human microphysiological liver models improves functionality and recapitulates hepatic zonation2023 | Lékařská fakulta v Hradci Králové
- A feasibility study of the toxic responses of human induced pluripotent stem cell-derived hepatocytes to phytochemicals2018 | Farmaceutická fakulta v Hradci Králové
- Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: Investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines2010 | Ústřední knihovna
- Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes2009 | Ústřední knihovna
- Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes2009 | Farmaceutická fakulta v Hradci Králové
- Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase Sensing in Human Hepatocytes2018 | Přírodovědecká fakulta
- Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling2018 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors2019 | Farmaceutická fakulta v Hradci Králové
- Plasma mannose-binding lectin is stimulated by PPAR alpha in humans2012 | 1. lékařská fakulta
- U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells2014 | Farmaceutická fakulta v Hradci Králové
- Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis2016 | Farmaceutická fakulta v Hradci Králové
- Steviol, an aglycone of steviol glycoside sweeteners, interacts with the pregnane X (PXR) and aryl hydrocarbon (AHR) receptors in detoxification regulation2017 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- Synthetic Stimulator of Interferon Genes (STING) Agonists Induce a Cytokine-Mediated Anti-Hepatitis B Virus Response in Nonparenchymal Liver Cells2023 | Ústřední knihovna, Přírodovědecká fakulta
- Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR)2015 | Farmaceutická fakulta v Hradci Králové
- Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines2013 | Farmaceutická fakulta v Hradci Králové
- Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models2018 | Farmaceutická fakulta v Hradci Králové
- Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain2020 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové, Fakulta tělesné výchovy a sportu
- Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation2023 | Farmaceutická fakulta v Hradci Králové
- Ellipticine oxidation and DNA adduct formation in human hepatocytes is catalyzed by human cytochromes P450 and enhanced by cytochrome b52012 | Přírodovědecká fakulta
- The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator2016 | Farmaceutická fakulta v Hradci Králové