- Study on 99mTc-MAG3 and 99mTc-DMSA renal accumulation using in vitro cellular model2011 | Farmaceutická fakulta v Hradci Králové
- The CRISPR-Cas9 crATIC HeLa transcriptome: Characterization of a novel cellular model of ATIC deficiency and ZMP accumulation2020 | 1. lékařská fakulta
- Expression of enzymes of metabolic activation of PAHs in rat liver cellular modelsPublikace bez příslušnosti k fakultě
- Molekulární charakterizace AdeI mutanta křeččích ovariálních buněk: buněčný model deficitu adenylosukcinát lyasy2011 | 1. lékařská fakulta
- Závěrečná konference doktorského projektu GAČR303/03/H065. Interdisciplinární přístup k molekulární podstatě dědičných poruch metabolismuPublikace bez příslušnosti k fakultě
- Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: Cellular models of de novo purine biosynthesis deficiency disorders2013 | 1. lékařská fakulta
- Validation of Freshly Isolated Rat Renal Cells as a Tool for Preclinical Assessment of Radiolabeled Receptor-Specific Peptide Uptake in the Kidney2023 | Farmaceutická fakulta v Hradci Králové
- CRISPR-Cas9 induced mutations along de novo purine synthesis in HeLa cells result in accumulation of individual enzyme substrates and affect purinosome formation2016 | 1. lékařská fakulta
- Cucurbitacin E Has Neuroprotective Properties and Autophagic Modulating Activities on Dopaminergic Neurons2014 | Farmaceutická fakulta v Hradci Králové
- Ensartinib (X-396) Effectively Modulates Pharmacokinetic Resistance Mediated by ABCB1 and ABCG2 Drug Efflux Transporters and CYP3A4 Biotransformation Enzyme2020 | Farmaceutická fakulta v Hradci Králové
- 2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease2021 | Publikace bez příslušnosti k fakultě
- Missense mutation in RPS7 causes Diamond-Blackfan anemia via alteration of erythrocyte metabolism, protein translation and induction of ribosomal stress2022 | Ústřední knihovna
- The CRISPR-Cas9 crADSL HeLa transcriptome: A first step in establishing a model for ADSL deficiency and SAICAR accumulation2019 | 1. lékařská fakulta
- Analysis of 5-Azacytidine Resistance Models Reveals a Set of Targetable Pathways2022 | 1. lékařská fakulta
- Transcriptome and metabolome analysis of crGART, a novel cell model of de novo purine synthesis deficiency: Alterations in CD36 expression and activity2021 | 1. lékařská fakulta
- Mitochondrial organization and structure are compromised in fibroblasts from patients with Huntington's disease2022 | 1. lékařská fakulta
- Exploring the molecular mechanisms used by human BK polyomavirus to activate immune responses in "reservoir cells"Publikace bez příslušnosti k fakultě
- In Vitro and In Vivo Experimental Hepatotoxic Models in Liver Research: Applications to the Assessment of Potential Hepatoprotective Drugs2016 | 1. lékařská fakulta
- Organoids as a personalized medicine tool for ultra-rare mutations in cystic fibrosis: The case of S955P and 1717-2A > G2020 | 2. lékařská fakulta
- Inhibition of AKR1B10-mediated metabolism of daunorubicin as a novel off-target effect for the Bcr-Abl tyrosine kinase inhibitor dasatinib2021 | Farmaceutická fakulta v Hradci Králové
- The Use of the LanthaScreen TR-FRET CAR Coactivator Assay in the Characterization of Constitutive Androstane Receptor (CAR) Inverse Agonists2015 | Farmaceutická fakulta v Hradci Králové
- The in vivo disposition and in vitro transmembrane transport of two model radiometabolites of DOTA-conjugated receptor-specific peptides labelled with Lu-1772015 | Farmaceutická fakulta v Hradci Králové
- Olaparib Synergizes the Anticancer Activity of Daunorubicin via Interaction with AKR1C32020 | Farmaceutická fakulta v Hradci Králové
- Entecavir Interacts with Influx Transporters hOAT1, hCNT2, hCNT3, but Not with hOCT2: The Potential for Renal Transporter-Mediated Cytotoxicity and Drug-Drug Interactions2016 | Farmaceutická fakulta v Hradci Králové
- X-Chromosome Inactivation Analysis in Different Cell Types and Induced Pluripotent Stem Cells Elucidates the Disease Mechanism in a Rare Case of Mucopolysaccharidosis Type II in a Female2016 | 1. lékařská fakulta
- Mathematical Models in the Description of Pregnane X Receptor (PXR)-Regulated Cytochrome P450 Enzyme Induction2018 | Farmaceutická fakulta v Hradci Králové, Přírodovědecká fakulta
- Cytochrome c Oxidase Subunit 4 Isoform Exchange Results in Modulation of Oxygen Affinity2020 | Přírodovědecká fakulta
- Talazoparib Does Not Interact with ABCB1 Transporter or Cytochrome P450s, but Modulates Multidrug Resistance Mediated by ABCC1 and ABCG2: An in Vitro and Ex Vivo Study2022 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- Brivanib Exhibits Potential for Pharmacokinetic Drug-Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes2019 | Farmaceutická fakulta v Hradci Králové
- Entrectinib reverses cytostatic resistance through the inhibition of ABCB1 efflux transporter, but not the CYP3A4 drug-metabolizing enzyme2020 | Farmaceutická fakulta v Hradci Králové