- Application of hepatic cytochrome b(5)/P450 reductase null (HBRN) mice to study the role of cytochrome b(5) in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine2019 | Přírodovědecká fakulta
- Photo-cytochrome b(5) - A New Tool to Study the Cytochrome P450 Electron-transport Chain2013 | Přírodovědecká fakulta
- Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b(5)2014 | Přírodovědecká fakulta, 2. lékařská fakulta
- NADH:Cytochrome b(5) Reductase and Cytochrome b(5) Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene2016 | Přírodovědecká fakulta
- Cytochrome b(5) impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b(5)/P450 reductase null (HBRN) mice2018 | Přírodovědecká fakulta
- Giardia intestinalis Incorporates Heme into Cytosolic Cytochrome b(5)2014 | Přírodovědecká fakulta
- Cytochrome b(5) plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine2017 | Přírodovědecká fakulta, 2. lékařská fakulta
- Induced expression of microsomal cytochrome b(5) determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I)2016 | Přírodovědecká fakulta
- Cytochrome b(5) Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases2012 | Přírodovědecká fakulta, 2. lékařská fakulta
- Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy2011 | Přírodovědecká fakulta
- Cytochrome b(5) Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases2012 | 2. lékařská fakulta
- The Anticancer Drug Ellipticine Induces Cytochromes P450 1A1, 1A2 and 3A, Cytochrome b(5) and NADPH:Cytochrome P450 Oxidoreductase in Rat Liver, Kidney and Lung2013 | Přírodovědecká fakulta
- Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b(5) Activity2020 | Přírodovědecká fakulta
- Cytochronne b(5) and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions2014 | Přírodovědecká fakulta, Ústřední knihovna
- The Hepatic Reductase Null (HRN (TM)) and Reductase Conditional Null (RCN) mouse models as suitable tools to study metabolism, toxicity and carcinogenicity of environmental pollutants2015 | Přírodovědecká fakulta
- NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A12016 | Př írodovědecká fakulta
- Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems2017 | Přírodovědecká fakulta
- Electrochemical Determination of Enzymes Metabolizing Ellipticine in Thyroid Cancer Cells - a Tool to Explain the Mechanism of Ellipticine Toxicity to these Cells2013 | Přírodovědecká fakulta, 2. lékařská fakulta
- Electrochemical Determination of Enzymes Metabolizing Ellipticine in Thyroid Cancer Cells - a Tool to Explain the Mechanism of Ellipticine Toxicity to these Cells2013 | Publikace bez příslušnosti k fakultě
- Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma2011 | 2. lékařská fakulta
- Exposure to benzo[a]pyrene of Hepatic Cytochrome P450 Reductase Null (HRN) and P450 Reductase Conditional Null (RCN) mice: Detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and P-32-postlabelling2012 | Přírodovědecká fakulta
- Photo-Methionine, Azidohomoalanine and Homopropargylglycine Are Incorporated into Newly Synthesized Proteins at Different Rates and Differentially Affect the Growth and Protein Expression Levels of Auxotrophic and Prototrophic E. coli in Minimal Medium2023 | Přírodovědecká fakulta
- The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers2016 | Přírodovědecká fakulta
- Human cytochrome-P450 enzymes metabolize N-(2-methoxyphenyl)hydroxylamine, a metabolite of the carcinogens o-anisidine and o-nitroanisole, thereby dictating its genotoxicity2011 | Přírodovědecká fakulta
- Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver2011 | 2. lékařská fakulta