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molecular modeling studies
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Studie lidského alfa(1)-kyselého glykoproteinu a jeho cukerné části pomocí Ramanovy optické aktivity a molekulárního modelování
2008 |
Matematicko-fyzikální fakulta
publication
An NMR and molecular modelling study of the bradykinin antagonists in micellar solution
1996 |
1. lékařská fakulta, Matematicko-fyzikální fakulta
publication
Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase
2021 |
Publikace bez příslušnosti k fakultě
publication
Drug-loading capacity of polylactide-based micro- and nanoparticles - Experimental and molecular modeling study
2020 |
1. lékařská fakulta
publication
7-Methoxytacrine-Adamantylamine Heterodimers as Cholinesterase Inhibitors in Alzheimer's Disease Treatment - Synthesis, Biological Evaluation and Molecular Modeling Studies
2013 |
Publikace bez příslušnosti k fakultě
publication
Evidence for the role of the alpha-helix in the xylosylation reactions involving the glycosaminoglycans-bearing serine of decorin DS-PGII as shown by 1H NMR, CD and molecular modeling studies
1996 |
1. lékařská fakulta, Matematicko-fyzikální fakulta
publication
Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D-2 3,4-dihydroquinolin-2(1H)-one Derivatives Related to Aripiprazole
2021 |
Publikace bez příslušnosti k fakultě
publication
Synthesis, in vitro acetylcholinesterase inhibitory activity and molecular docking of new acridine-coumarin hybrids
2017 |
Publikace bez příslušnosti k fakultě
publication
Preparation, In Vitro Screening and Molecular Modelling of Monoquaternary Compounds Related to the Selective Acetylcholinesterase Inhibitor BW284c51
2015 |
Publikace bez příslušnosti k fakultě
publication
Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors - implications for early Myasthenia gravis treatment
2011 |
Publikace bez příslušnosti k fakultě
publication
7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment
2015 |
Publikace bez příslušnosti k fakultě
publication
Preparation, in vitro evaluation and molecular modelling of pyridinium-quinolinium/isoquinolinium non-symmetrical bisquaternary cholinesterase inhibitors
2013 |
Farmaceutická fakulta v Hradci Králové
publication
Monooxime bispyridinium reactivators bearing xylene linker synthesis and in vitro evaluation on model of organophosphate-inhibited acetylcholinesterase
2016 |
Farmaceutická fakulta v Hradci Králové
publication
Preparation of 7-Methoxy Tacrine Dimer Analogs and Their In vitro/In silico Evaluation as Potential Cholinesterase Inhibitors
2015 |
Publikace bez příslušnosti k fakultě
publication
7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies
2014 |
Farmaceutická fakulta v Hradci Králové, Přírodovědecká fakulta
publication
Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity
2015 |
Publikace bez příslušnosti k fakultě
publication
Novel Group of AChE Reactivators-Synthesis, In Vitro Reactivation and Molecular Docking Study
2018 |
Publikace bez příslušnosti k fakultě
publication
Pralidoxime-like reactivator with increased lipophilicity- Molecular modeling and in vitro study
2023 |
Publikace bez příslušnosti k fakultě
publication
Development of small bisquaternary cholinesterase inhibitors as drugs for pre-treatment of nerve agent poisonings
2018 |
Publikace bez příslušnosti k fakultě
publication
Tacrine-coumarin and Tacrine-7-chloroquinoline Hybrids with Thiourea Linkers: Cholinesterase Inhibition Properties, Kinetic Study, Molecular Docking and Permeability Assay for Blood-brain Barrier
2018 |
Publikace bez příslušnosti k fakultě
publication
Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives
2019 |
Publikace bez příslušnosti k fakultě
publication
Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation
2017 |
Publikace bez příslušnosti k fakultě
publication
Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells
2021 |
Publikace bez příslušnosti k fakultě
publication
2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1
2023 |
Farmaceutická fakulta v Hradci Králové
publication
Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment
2021 |
Publikace bez příslušnosti k fakultě